ENSG00000108219


Homo sapiens

Features
Gene ID: ENSG00000108219
  
Biological name :TSPAN14
  
Synonyms : Q8NG11 / tetraspanin 14 / TSPAN14
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q23.1
Gene start: 80454166
Gene end: 80533123
  
Corresponding Affymetrix probe sets: 221002_s_at (Human Genome U133 Plus 2.0 Array)   223314_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418195
Ensembl peptide - ENSP00000480263
Ensembl peptide - ENSP00000344076
Ensembl peptide - ENSP00000361229
Ensembl peptide - ENSP00000361230
Ensembl peptide - ENSP00000361231
Ensembl peptide - ENSP00000361237
Ensembl peptide - ENSP00000396270
NCBI entrez gene - 81619     See in Manteia.
RefSeq - XM_017016713
RefSeq - NM_030927
RefSeq - XM_006717992
RefSeq - XM_011540219
RefSeq - XM_011540220
RefSeq - XM_011540221
RefSeq - XM_011540222
RefSeq - XM_017016707
RefSeq - XM_017016708
RefSeq - XM_017016709
RefSeq - XM_017016710
RefSeq - XM_017016711
RefSeq - XM_017016712
RefSeq - NM_001128309
RefSeq Peptide - NP_112189
RefSeq Peptide - NP_001338199
RefSeq Peptide - NP_001338200
RefSeq Peptide - NP_001338201
RefSeq Peptide - NP_001121781
RefSeq Peptide - NP_001338195
RefSeq Peptide - NP_001338196
RefSeq Peptide - NP_001338197
RefSeq Peptide - NP_001338198
swissprot - Q8NG11
swissprot - A6NEP9
swissprot - H7BXY6
Ensembl - ENSG00000108219
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tspan14ENSDARG00000055938Danio rerio
 TSPAN14ENSGALG00000002414Gallus gallus
 Q8QZY6ENSMUSG00000037824Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96FV3 / TSPAN17 / tetraspanin 17ENSG0000004814058
P62079 / TSPAN5 / tetraspanin 5ENSG0000016878557
Q86UF1 / TSPAN33 / tetraspanin 33ENSG0000015845739
TSPAN10 / tetraspanin 10ENSG0000018261232
O95858 / TSPAN15 / tetraspanin 15ENSG0000009928231
CD63 / P08962 / CD63 moleculeENSG0000013540426
A1L157 / TSPAN11 / tetraspanin 11ENSG0000011090023
O43657 / TSPAN6 / tetraspanin 6ENSG0000000000323
P41732 / TSPAN7 / tetraspanin 7ENSG0000015629823
CD151 / P48509 / CD151 molecule (Raph blood group)ENSG0000017769723
AF241726.2ENSG0000025034921
O60637 / TSPAN3 / tetraspanin 3ENSG0000014039120


Protein motifs (from Interpro)
Interpro ID Name
 IPR000301  Tetraspanin
 IPR008952  Tetraspanin, EC2 domain superfamily
 IPR018499  Tetraspanin/Peripherin
 IPR018503  Tetraspanin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045747 positive regulation of Notch signaling pathway IMP
 biological_processGO:0051604 protein maturation IMP
 biological_processGO:0072659 protein localization to plasma membrane IMP
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0070821 tertiary granule membrane TAS
 cellular_componentGO:0097197 tetraspanin-enriched microdomain IEA
 molecular_functionGO:0019899 enzyme binding IPI


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000137845 ADAM10 / O14672 / ADAM metallopeptidase domain 10  / reaction / complex






 

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