ENSG00000135404


Homo sapiens

Features
Gene ID: ENSG00000135404
  
Biological name :CD63
  
Synonyms : CD63 / CD63 molecule / P08962
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.2
Gene start: 55725323
Gene end: 55729707
  
Corresponding Affymetrix probe sets: 200663_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000449684
Ensembl peptide - ENSP00000449654
Ensembl peptide - ENSP00000450191
Ensembl peptide - ENSP00000257857
Ensembl peptide - ENSP00000393502
Ensembl peptide - ENSP00000446752
Ensembl peptide - ENSP00000446807
Ensembl peptide - ENSP00000447356
Ensembl peptide - ENSP00000447730
Ensembl peptide - ENSP00000447938
Ensembl peptide - ENSP00000448091
Ensembl peptide - ENSP00000449281
Ensembl peptide - ENSP00000449337
Ensembl peptide - ENSP00000449435
NCBI entrez gene - 967     See in Manteia.
OMIM - 155740
RefSeq - NM_001257390
RefSeq - NM_001257392
RefSeq - NM_001257400
RefSeq - NM_001257401
RefSeq - NM_001267698
RefSeq - NM_001780
RefSeq - NM_001257389
RefSeq - NM_001257391
RefSeq Peptide - NP_001244319
RefSeq Peptide - NP_001244321
RefSeq Peptide - NP_001244329
RefSeq Peptide - NP_001244330
RefSeq Peptide - NP_001254627
RefSeq Peptide - NP_001771
RefSeq Peptide - NP_001244318
RefSeq Peptide - NP_001244320
swissprot - P08962
swissprot - A0A024RB05
swissprot - F8VNT9
swissprot - F8VV56
swissprot - F8VWK8
swissprot - F8VX62
swissprot - F8W022
Ensembl - ENSG00000135404
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cd63ENSDARG00000025147Danio rerio
 Cd63ENSMUSG00000025351Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q86UF1 / TSPAN33 / tetraspanin 33ENSG0000015845731
P41732 / TSPAN7 / tetraspanin 7ENSG0000015629831
O60637 / TSPAN3 / tetraspanin 3ENSG0000014039131
Q96FV3 / TSPAN17 / tetraspanin 17ENSG0000004814030
CD151 / P48509 / CD151 molecule (Raph blood group)ENSG0000017769729
AF241726.2ENSG0000025034929
Q8NG11 / TSPAN14 / tetraspanin 14ENSG0000010821929
A1L157 / TSPAN11 / tetraspanin 11ENSG0000011090028
O43657 / TSPAN6 / tetraspanin 6ENSG0000000000328
P62079 / TSPAN5 / tetraspanin 5ENSG0000016878527
O95858 / TSPAN15 / tetraspanin 15ENSG0000009928224
TSPAN10 / tetraspanin 10ENSG0000018261222


Protein motifs (from Interpro)
Interpro ID Name
 IPR000301  Tetraspanin
 IPR008952  Tetraspanin, EC2 domain superfamily
 IPR018499  Tetraspanin/Peripherin
 IPR018503  Tetraspanin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002092 positive regulation of receptor internalization IMP
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0007160 cell-matrix adhesion IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016477 cell migration IMP
 biological_processGO:0034613 cellular protein localization IDA
 biological_processGO:0035646 endosome to melanosome transport IMP
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0043473 pigmentation IEA
 biological_processGO:0048757 pigment granule maturation IMP
 biological_processGO:0050931 pigment cell differentiation IEA
 biological_processGO:1900746 regulation of vascular endothelial growth factor signaling pathway IMP
 biological_processGO:1901379 regulation of potassium ion transmembrane transport IDA
 biological_processGO:2001046 positive regulation of integrin-mediated signaling pathway IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane TAS
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005771 multivesicular body IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0010008 endosome membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031088 platelet dense granule membrane TAS
 cellular_componentGO:0031226 intrinsic component of plasma membrane IDA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0031904 endosome lumen IDA
 cellular_componentGO:0032585 multivesicular body membrane IDA
 cellular_componentGO:0035577 azurophil granule membrane TAS
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0070062 extracellular exosome IEA
 cellular_componentGO:0097487 multivesicular body, internal vesicle IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Platelet degranulation
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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