ENSG00000168785


Homo sapiens

Features
Gene ID: ENSG00000168785
  
Biological name :TSPAN5
  
Synonyms : P62079 / tetraspanin 5 / TSPAN5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q23
Gene start: 98470367
Gene end: 98658629
  
Corresponding Affymetrix probe sets: 209890_at (Human Genome U133 Plus 2.0 Array)   225387_at (Human Genome U133 Plus 2.0 Array)   225388_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000307701
Ensembl peptide - ENSP00000426248
Ensembl peptide - ENSP00000423916
Ensembl peptide - ENSP00000423504
Ensembl peptide - ENSP00000422548
Ensembl peptide - ENSP00000422351
Ensembl peptide - ENSP00000421808
NCBI entrez gene - 10098     See in Manteia.
OMIM - 613136
RefSeq - XM_005262680
RefSeq - NM_005723
RefSeq Peptide - NP_005714
swissprot - B7Z317
swissprot - D6RBT5
swissprot - H0Y8W4
swissprot - D6RGZ7
swissprot - P62079
swissprot - D6R9N6
swissprot - D6RAR1
Ensembl - ENSG00000168785
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tspan5aENSDARG00000086033Danio rerio
 tspan5bENSDARG00000070449Danio rerio
 TSPAN5ENSGALG00000012227Gallus gallus
 P62080ENSMUSG00000028152Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96FV3 / TSPAN17 / tetraspanin 17ENSG0000004814079
Q8NG11 / TSPAN14 / tetraspanin 14ENSG0000010821958
Q86UF1 / TSPAN33 / tetraspanin 33ENSG0000015845742
TSPAN10 / tetraspanin 10ENSG0000018261234
O95858 / TSPAN15 / tetraspanin 15ENSG0000009928232
A1L157 / TSPAN11 / tetraspanin 11ENSG0000011090026
P41732 / TSPAN7 / tetraspanin 7ENSG0000015629825
CD151 / P48509 / CD151 molecule (Raph blood group)ENSG0000017769725
O43657 / TSPAN6 / tetraspanin 6ENSG0000000000325
CD63 / P08962 / CD63 moleculeENSG0000013540424
AF241726.2ENSG0000025034924
O60637 / TSPAN3 / tetraspanin 3ENSG0000014039121


Protein motifs (from Interpro)
Interpro ID Name
 IPR000301  Tetraspanin
 IPR008952  Tetraspanin, EC2 domain superfamily
 IPR018499  Tetraspanin/Peripherin
 IPR018503  Tetraspanin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045747 positive regulation of Notch signaling pathway IMP
 biological_processGO:0051604 protein maturation IEA
 biological_processGO:0072659 protein localization to plasma membrane IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0019899 enzyme binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000137845 ADAM10 / O14672 / ADAM metallopeptidase domain 10  / complex / reaction






 

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