ENSG00000108510


Homo sapiens

Features
Gene ID: ENSG00000108510
  
Biological name :MED13
  
Synonyms : MED13 / mediator complex subunit 13 / Q9UHV7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q23.2
Gene start: 61942605
Gene end: 62065282
  
Corresponding Affymetrix probe sets: 201986_at (Human Genome U133 Plus 2.0 Array)   201987_at (Human Genome U133 Plus 2.0 Array)   223780_s_at (Human Genome U133 Plus 2.0 Array)   244611_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464131
Ensembl peptide - ENSP00000380888
NCBI entrez gene - 9969     See in Manteia.
OMIM - 603808
RefSeq - XM_011525553
RefSeq - NM_005121
RefSeq - XM_011525551
RefSeq - XM_011525552
RefSeq Peptide - NP_005112
swissprot - Q9UHV7
swissprot - J3QRB7
swissprot - A0A024QZ75
Ensembl - ENSG00000108510
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 med13aENSDARG00000053884Danio rerio
 med13bENSDARG00000003910Danio rerio
 MED13ENSGALG00000005230Gallus gallus
 Med13ENSMUSG00000034297Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MED13L / Q71F56 / mediator complex subunit 13 likeENSG0000012306653


Protein motifs (from Interpro)
Interpro ID Name
 IPR009401  Mediator complex, subunit Med13
 IPR021643  Mediator complex, subunit Med13, N-terminal, metazoa/fungi


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0030518 intracellular steroid hormone receptor signaling pathway IDA
 biological_processGO:0030521 androgen receptor signaling pathway IDA
 biological_processGO:0042632 cholesterol homeostasis IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0070328 triglyceride homeostasis IEA
 biological_processGO:1904168 negative regulation of thyroid hormone receptor activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016592 mediator complex IDA
 molecular_functionGO:0003712 transcription coregulator activity IDA
 molecular_functionGO:0003713 transcription coactivator activity IDA
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity NAS
 molecular_functionGO:0042809 vitamin D receptor binding NAS
 molecular_functionGO:0046966 thyroid hormone receptor binding IDA


Pathways (from Reactome)
Pathway description
PPARA activates gene expression
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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