ENSG00000110237


Homo sapiens

Features
Gene ID: ENSG00000110237
  
Biological name :ARHGEF17
  
Synonyms : ARHGEF17 / Q96PE2 / Rho guanine nucleotide exchange factor 17
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.4
Gene start: 73308289
Gene end: 73369388
  
Corresponding Affymetrix probe sets: 203756_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000263674
Ensembl peptide - ENSP00000441135
Ensembl peptide - ENSP00000493940
NCBI entrez gene - 9828     See in Manteia.
OMIM - 617043
RefSeq - XM_017018624
RefSeq - NM_014786
RefSeq - XM_017018623
RefSeq Peptide - NP_055601
swissprot - Q96PE2
swissprot - H0YFZ8
Ensembl - ENSG00000110237
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARHGEF17ENSDARG00000101644Danio rerio
 ENSGALG00000017326Gallus gallus
 Q80U35ENSMUSG00000032875Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UPT6 / MAPK8IP3 / mitogen-activated protein kinase 8 interacting protein 3ENSG0000013883415
SPAG9 / O60271 / sperm associated antigen 9ENSG0000000829415
Q9HCE6 / ARHGEF10L / Rho guanine nucleotide exchange factor 10 likeENSG0000007496413
O15013 / ARHGEF10 / Rho guanine nucleotide exchange factor 10ENSG0000010472812


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR011993  PH-like domain superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR035899  Dbl homology (DH) domain superfamily
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0030036 actin cytoskeleton organization IDA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0043065 positive regulation of apoptotic process TAS
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IDA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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