ENSMUSG00000032875


Mus musculus

Features
Gene ID: ENSMUSG00000032875
  
Biological name :Arhgef17
  
Synonyms : Arhgef17 / Q80U35 / Rho guanine nucleotide exchange factor 17
  
Possible biological names infered from orthology : Q96PE2
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: E2
Gene start: 100869752
Gene end: 100932107
  
Corresponding Affymetrix probe sets: 10565935 (MoGene1.0st)   1419938_s_at (Mouse Genome 430 2.0 Array)   1419939_at (Mouse Genome 430 2.0 Array)   1433682_at (Mouse Genome 430 2.0 Array)   1442357_at (Mouse Genome 430 2.0 Array)   1447441_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000146564
Ensembl peptide - ENSMUSP00000146907
Ensembl peptide - ENSMUSP00000102647
NCBI entrez gene - 207212     See in Manteia.
MGI - MGI:2673002
RefSeq - NM_001081116
RefSeq Peptide - NP_001074585
swissprot - A0A140LIQ0
swissprot - Q80U35
Ensembl - ENSMUSG00000032875
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARHGEF17ENSDARG00000101644Danio rerio
 ENSGALG00000017326Gallus gallus
 Q96PE2ENSG00000110237Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Spag9 / Q58A65 / sperm associated antigen 9 / O60271*ENSMUSG0000002085915
Q9ESN9 / Mapk8ip3 / C-Jun-amino-terminal kinase-interacting protein 3 / Q9UPT6* / mitogen-activated protein kinase 8 interacting protein 3*ENSMUSG0000002416314
A2AWP8 / Arhgef10l / Rho guanine nucleotide exchange factor 10-like protein / Q9HCE6* / Rho guanine nucleotide exchange factor 10 like*ENSMUSG0000004096413
Q8C033 / Arhgef10 / Rho guanine nucleotide exchange factor 10 / O15013*ENSMUSG0000007117612


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR011993  PH-like domain superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR035899  Dbl homology (DH) domain superfamily
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030036 actin cytoskeleton organization ISO
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity ISO
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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