ENSMUSG00000071176


Mus musculus

Features
Gene ID: ENSMUSG00000071176
  
Biological name :Arhgef10
  
Synonyms : Arhgef10 / Q8C033 / Rho guanine nucleotide exchange factor 10
  
Possible biological names infered from orthology : O15013
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: A1.1
Gene start: 14911663
Gene end: 15001085
  
Corresponding Affymetrix probe sets: 10570483 (MoGene1.0st)   1446374_at (Mouse Genome 430 2.0 Array)   1452302_at (Mouse Genome 430 2.0 Array)   1452303_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000081225
Ensembl peptide - ENSMUSP00000106424
Ensembl peptide - ENSMUSP00000125526
Ensembl peptide - ENSMUSP00000125606
NCBI entrez gene - 234094     See in Manteia.
MGI - MGI:2444453
RefSeq - XM_017312673
RefSeq - XM_017312668
RefSeq - XM_017312669
RefSeq - XM_017312670
RefSeq - XM_017312671
RefSeq - XM_017312672
RefSeq - NM_001037736
RefSeq - NM_172751
RefSeq - XM_006508768
RefSeq - XM_006508770
RefSeq - XM_006508771
RefSeq - XM_006508772
RefSeq Peptide - NP_001032825
RefSeq Peptide - NP_766339
swissprot - F7BQE4
swissprot - Q8C033
swissprot - F7BCP8
Ensembl - ENSMUSG00000071176
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgef10ENSDARG00000077788Danio rerio
 ARHGEF10ENSGALG00000016350Gallus gallus
 O15013ENSG00000104728Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A2AWP8 / Arhgef10l / Rho guanine nucleotide exchange factor 10-like protein / Q9HCE6* / Rho guanine nucleotide exchange factor 10 like*ENSMUSG0000004096440
Q80U35 / Arhgef17 / Rho guanine nucleotide exchange factor 17 / Q96PE2*ENSMUSG0000003287519
Q9ESN9 / Mapk8ip3 / C-Jun-amino-terminal kinase-interacting protein 3 / Q9UPT6* / mitogen-activated protein kinase 8 interacting protein 3*ENSMUSG0000002416314
Spag9 / Q58A65 / sperm associated antigen 9 / O60271*ENSMUSG0000002085914


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR011993  PH-like domain superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR030632  Rho guanine nucleotide exchange factor 10
 IPR035899  Dbl homology (DH) domain superfamily
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0022011 myelination in peripheral nervous system IEA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0051298 centrosome duplication ISO
 biological_processGO:0051496 positive regulation of stress fiber assembly ISO
 biological_processGO:0090307 mitotic spindle assembly IEA
 biological_processGO:0090630 activation of GTPase activity ISO
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019894 kinesin binding ISO


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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