ENSMUSG00000040964


Mus musculus

Features
Gene ID: ENSMUSG00000040964
  
Biological name :Arhgef10l
  
Synonyms : A2AWP8 / Arhgef10l / Rho guanine nucleotide exchange factor 10-like protein
  
Possible biological names infered from orthology : Q9HCE6 / Rho guanine nucleotide exchange factor 10 like
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D3
Gene start: 140514485
Gene end: 140666012
  
Corresponding Affymetrix probe sets: 10517744 (MoGene1.0st)   1460405_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117038
Ensembl peptide - ENSMUSP00000101425
Ensembl peptide - ENSMUSP00000119471
Ensembl peptide - ENSMUSP00000123642
Ensembl peptide - ENSMUSP00000122667
Ensembl peptide - ENSMUSP00000120437
Ensembl peptide - ENSMUSP00000040531
Ensembl peptide - ENSMUSP00000066249
Ensembl peptide - ENSMUSP00000095431
Ensembl peptide - ENSMUSP00000101423
Ensembl peptide - ENSMUSP00000101424
NCBI entrez gene - 72754     See in Manteia.
MGI - MGI:1920004
RefSeq - XM_017320397
RefSeq - NM_001112722
RefSeq - NM_001112723
RefSeq - NM_001290803
RefSeq - NM_172415
RefSeq - XM_006539201
RefSeq - XM_006539202
RefSeq - XM_006539204
RefSeq - XM_011250337
RefSeq - XM_011250340
RefSeq - XM_017320396
RefSeq Peptide - NP_001106194
RefSeq Peptide - NP_001277732
RefSeq Peptide - NP_766003
RefSeq Peptide - NP_001106193
swissprot - F6S3V7
swissprot - F6ZH54
swissprot - A2AWP6
swissprot - A2AWP4
swissprot - A8Y5U3
swissprot - A2AWP8
swissprot - A2AWP7
Ensembl - ENSMUSG00000040964
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgef10laENSDARG00000088630Danio rerio
 arhgef10lbENSDARG00000074244Danio rerio
 ARHGEF10LENSGALG00000043128Gallus gallus
 Q9HCE6ENSG00000074964Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8C033 / Arhgef10 / Rho guanine nucleotide exchange factor 10 / O15013*ENSMUSG0000007117642
Q80U35 / Arhgef17 / Rho guanine nucleotide exchange factor 17 / Q96PE2*ENSMUSG0000003287521
Q9ESN9 / Mapk8ip3 / C-Jun-amino-terminal kinase-interacting protein 3 / Q9UPT6* / mitogen-activated protein kinase 8 interacting protein 3*ENSMUSG0000002416315
Spag9 / Q58A65 / sperm associated antigen 9 / O60271*ENSMUSG0000002085915


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR011993  PH-like domain superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR035899  Dbl homology (DH) domain superfamily
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032933 SREBP signaling pathway ISO
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051496 positive regulation of stress fiber assembly ISO
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISO
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005096 GTPase activator activity ISO
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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