ENSG00000138834


Homo sapiens

Features
Gene ID: ENSG00000138834
  
Biological name :MAPK8IP3
  
Synonyms : MAPK8IP3 / mitogen-activated protein kinase 8 interacting protein 3 / Q9UPT6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p13.3
Gene start: 1706183
Gene end: 1770317
  
Corresponding Affymetrix probe sets: 213177_at (Human Genome U133 Plus 2.0 Array)   213178_s_at (Human Genome U133 Plus 2.0 Array)   216137_s_at (Human Genome U133 Plus 2.0 Array)   216139_s_at (Human Genome U133 Plus 2.0 Array)   230162_s_at (Human Genome U133 Plus 2.0 Array)   232085_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000454739
Ensembl peptide - ENSP00000481780
Ensembl peptide - ENSP00000250894
Ensembl peptide - ENSP00000348290
NCBI entrez gene - 23162     See in Manteia.
OMIM - 605431
RefSeq - XM_017023081
RefSeq - XM_011522429
RefSeq - XM_011522430
RefSeq - XM_011522431
RefSeq - XM_011522432
RefSeq - XM_011522433
RefSeq - XM_017023079
RefSeq - XM_017023080
RefSeq - NM_001040439
RefSeq - NM_001318852
RefSeq - NM_015133
RefSeq - XM_005255190
RefSeq - XM_006720869
RefSeq Peptide - NP_055948
RefSeq Peptide - NP_001035529
RefSeq Peptide - NP_001305781
swissprot - A0A087WYG2
swissprot - Q9UPT6
swissprot - H3BN91
swissprot - E9PFH7
Ensembl - ENSG00000138834
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mapk8ip3ENSDARG00000062531Danio rerio
 Q9ESN9ENSMUSG00000024163Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SPAG9 / O60271 / sperm associated antigen 9ENSG0000000829458
Q96PE2 / ARHGEF17 / Rho guanine nucleotide exchange factor 17ENSG0000011023722
Q9HCE6 / ARHGEF10L / Rho guanine nucleotide exchange factor 10 likeENSG0000007496414
O15013 / ARHGEF10 / Rho guanine nucleotide exchange factor 10ENSG0000010472814


Protein motifs (from Interpro)
Interpro ID Name
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR019143  JNK/Rab-associated protein-1, N-terminal
 IPR027267  AH/BAR domain superfamily
 IPR032486  JNK-interacting protein, leucine zipper II
 IPR034743  RH1 domain
 IPR034744  RH2 domain
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0007254 JNK cascade IEA
 biological_processGO:0007257 activation of JUN kinase activity IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0007585 respiratory gaseous exchange IEA
 biological_processGO:0008104 protein localization IEA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0043507 positive regulation of JUN kinase activity IEA
 biological_processGO:0045666 positive regulation of neuron differentiation IEA
 biological_processGO:0046328 regulation of JNK cascade IEA
 biological_processGO:0048286 lung alveolus development IEA
 biological_processGO:0060425 lung morphogenesis IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005790 smooth endoplasmic reticulum IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0030673 axolemma IEA
 cellular_componentGO:0043005 neuron projection IEA
 molecular_functionGO:0005078 MAP-kinase scaffold activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008432 JUN kinase binding IEA
 molecular_functionGO:0019894 kinesin binding IEA
 molecular_functionGO:0030159 receptor signaling complex scaffold activity IBA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IEA
 molecular_functionGO:0031435 mitogen-activated protein kinase kinase kinase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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