ENSG00000110786


Homo sapiens

Features
Gene ID: ENSG00000110786
  
Biological name :PTPN5
  
Synonyms : P54829 / protein tyrosine phosphatase, non-receptor type 5 / PTPN5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p15.1
Gene start: 18727928
Gene end: 18792721
  
Corresponding Affymetrix probe sets: 233470_at (Human Genome U133 Plus 2.0 Array)   233471_at (Human Genome U133 Plus 2.0 Array)   236456_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000435056
Ensembl peptide - ENSP00000379469
Ensembl peptide - ENSP00000379471
Ensembl peptide - ENSP00000379473
Ensembl peptide - ENSP00000351342
NCBI entrez gene - 84867     See in Manteia.
OMIM - 176879
RefSeq - XM_017018441
RefSeq - NM_032781
RefSeq - XM_011520411
RefSeq - XM_017018434
RefSeq - XM_017018435
RefSeq - XM_017018436
RefSeq - XM_017018437
RefSeq - XM_017018438
RefSeq - XM_017018439
RefSeq - XM_017018440
RefSeq - NM_001039970
RefSeq - NM_001278236
RefSeq - NM_001278238
RefSeq - NM_001278239
RefSeq - NM_006906
RefSeq Peptide - NP_001265165
RefSeq Peptide - NP_001265167
RefSeq Peptide - NP_001265168
RefSeq Peptide - NP_008837
RefSeq Peptide - NP_116170
RefSeq Peptide - NP_001035059
swissprot - A8MXF1
swissprot - E9PLZ4
swissprot - P54829
Ensembl - ENSG00000110786
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptpn5ENSDARG00000074866Danio rerio
 PTPN5ENSGALG00000006368Gallus gallus
 Ptpn5ENSMUSG00000030854Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTPRR / Q15256 / protein tyrosine phosphatase, receptor type RENSG0000015323343
PTPN7 / P35236 / protein tyrosine phosphatase, non-receptor type 7ENSG0000014385133
PTPN11 / Q06124 / protein tyrosine phosphatase, non-receptor type 11ENSG0000017929524
PTPRN / Q16849 / protein tyrosine phosphatase, receptor type NENSG0000005435623
PTPRN2 / Q92932 / protein tyrosine phosphatase, receptor type N2ENSG0000015509322
PTPN6 / P29350 / protein tyrosine phosphatase, non-receptor type 6ENSG0000011167922


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR008356  Protein-tyrosine phosphatase, KIM-containing
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR016334  Protein-tyrosine phosphatase, receptor type R/non-receptor type 5
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation TAS
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0071345 cellular response to cytokine stimulus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 molecular_functionGO:0001784 phosphotyrosine residue binding IDA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Interleukin-37 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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