ENSG00000155093


Homo sapiens

Features
Gene ID: ENSG00000155093
  
Biological name :PTPRN2
  
Synonyms : protein tyrosine phosphatase, receptor type N2 / PTPRN2 / Q92932
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q36.3
Gene start: 157539056
Gene end: 158587788
  
Corresponding Affymetrix probe sets: 203029_s_at (Human Genome U133 Plus 2.0 Array)   203030_s_at (Human Genome U133 Plus 2.0 Array)   211534_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000387114
Ensembl peptide - ENSP00000374067
Ensembl peptide - ENSP00000374069
Ensembl peptide - ENSP00000385464
Ensembl peptide - ENSP00000374064
NCBI entrez gene - 5799     See in Manteia.
OMIM - 601698
RefSeq - XM_017012476
RefSeq - NM_001308267
RefSeq - NM_001308268
RefSeq - NM_002847
RefSeq - NM_130842
RefSeq - NM_130843
RefSeq - XM_011516446
RefSeq - XM_011516449
RefSeq - XM_017012475
RefSeq Peptide - NP_570857
RefSeq Peptide - NP_001295196
RefSeq Peptide - NP_001295197
RefSeq Peptide - NP_570858
RefSeq Peptide - NP_002838
swissprot - Q92932
swissprot - E7EM83
swissprot - A0A0A0MSD7
Ensembl - ENSG00000155093
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptprn2ENSDARG00000035970Danio rerio
 PTPRN2ENSGALG00000030054Gallus gallus
 P80560ENSMUSG00000056553Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTPRN / Q16849 / protein tyrosine phosphatase, receptor type NENSG0000005435642
PTPN11 / Q06124 / protein tyrosine phosphatase, non-receptor type 11ENSG0000017929514
PTPRR / Q15256 / protein tyrosine phosphatase, receptor type RENSG0000015323313
PTPN6 / P29350 / protein tyrosine phosphatase, non-receptor type 6ENSG0000011167913
PTPN5 / P54829 / protein tyrosine phosphatase, non-receptor type 5ENSG0000011078612
PTPN7 / P35236 / protein tyrosine phosphatase, non-receptor type 7ENSG0000014385111


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR021613  Protein-tyrosine phosphatase receptor IA-2 ectodomain
 IPR029021  Protein-tyrosine phosphatase-like
 IPR029403  RESP18 domain
 IPR033522  Receptor-type tyrosine-protein phosphatase-like N/N2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0007269 neurotransmitter secretion IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0034260 negative regulation of GTPase activity IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0035773 insulin secretion involved in cellular response to glucose stimulus IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030141 secretory granule IEA
 cellular_componentGO:0030658 transport vesicle membrane IEA
 cellular_componentGO:0030667 secretory granule membrane IEA
 cellular_componentGO:0030672 synaptic vesicle membrane ISS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043195 terminal bouton IEA
 cellular_componentGO:0043235 receptor complex IDA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0101003 ficolin-1-rich granule membrane TAS
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005001 transmembrane receptor protein tyrosine phosphatase activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr