ENSG00000111605


Homo sapiens

Features
Gene ID: ENSG00000111605
  
Biological name :CPSF6
  
Synonyms : cleavage and polyadenylation specific factor 6 / CPSF6 / Q16630
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q15
Gene start: 69239537
Gene end: 69274358
  
Corresponding Affymetrix probe sets: 202469_s_at (Human Genome U133 Plus 2.0 Array)   202470_s_at (Human Genome U133 Plus 2.0 Array)   226934_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000391437
Ensembl peptide - ENSP00000446670
Ensembl peptide - ENSP00000450206
Ensembl peptide - ENSP00000266679
Ensembl peptide - ENSP00000391774
NCBI entrez gene - 11052     See in Manteia.
OMIM - 604979
RefSeq - XM_005268590
RefSeq - NM_001300947
RefSeq - NM_007007
RefSeq - XM_005268588
RefSeq Peptide - NP_001287876
RefSeq Peptide - NP_008938
swissprot - F8VNP8
swissprot - F8W084
swissprot - F8WJN3
swissprot - Q16630
Ensembl - ENSG00000111605
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cpsf6ENSDARG00000018618Danio rerio
 CPSF6ENSGALG00000019355Gallus gallus
 Cpsf6ENSMUSG00000055531Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CPSF7 / Q8N684 / cleavage and polyadenylation specific factor 7ENSG0000014953241


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR034769  Cleavage and polyadenylation specificity factor subunit 6
 IPR034772  CPSF6/7 family
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006378 mRNA polyadenylation IMP
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0046833 positive regulation of RNA export from nucleus IMP
 biological_processGO:0051262 protein tetramerization IDA
 biological_processGO:0051290 protein heterotetramerization IDA
 biological_processGO:0098789 pre-mRNA cleavage required for polyadenylation IMP
 biological_processGO:1990120 messenger ribonucleoprotein complex assembly IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005726 perichromatin fibrils IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005847 mRNA cleavage and polyadenylation specificity factor complex IDA
 cellular_componentGO:0005849 mRNA cleavage factor complex IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0035061 interchromatin granule IDA
 cellular_componentGO:0042382 paraspeckles IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043023 ribosomal large subunit binding IDA
 molecular_functionGO:1990448 exon-exon junction complex binding IDA


Pathways (from Reactome)
Pathway description
Signaling by cytosolic FGFR1 fusion mutants
Signaling by FGFR1 in disease


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000111605 CPSF6 / Q16630 / cleavage and polyadenylation specific factor 6  / complex






 

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