ENSG00000149532


Homo sapiens

Features
Gene ID: ENSG00000149532
  
Biological name :CPSF7
  
Synonyms : cleavage and polyadenylation specific factor 7 / CPSF7 / Q8N684
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q12.2
Gene start: 61402641
Gene end: 61430031
  
Corresponding Affymetrix probe sets: 217866_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000443504
Ensembl peptide - ENSP00000446193
Ensembl peptide - ENSP00000487286
Ensembl peptide - ENSP00000446330
Ensembl peptide - ENSP00000345412
Ensembl peptide - ENSP00000378352
Ensembl peptide - ENSP00000391359
Ensembl peptide - ENSP00000392400
Ensembl peptide - ENSP00000393828
Ensembl peptide - ENSP00000397203
Ensembl peptide - ENSP00000407394
Ensembl peptide - ENSP00000414295
Ensembl peptide - ENSP00000437467
Ensembl peptide - ENSP00000437531
Ensembl peptide - ENSP00000437768
Ensembl peptide - ENSP00000437860
Ensembl peptide - ENSP00000438381
Ensembl peptide - ENSP00000440414
Ensembl peptide - ENSP00000442819
NCBI entrez gene - 79869     See in Manteia.
RefSeq - XM_017018345
RefSeq - NM_001136040
RefSeq - NM_001142565
RefSeq - NM_024811
RefSeq - XM_005274298
RefSeq - XM_005274299
RefSeq - XM_005274303
RefSeq - XM_011545257
RefSeq - XM_011545258
RefSeq - XM_011545259
RefSeq - XM_011545260
RefSeq - XM_011545261
RefSeq - XM_011545262
RefSeq - XM_011545263
RefSeq Peptide - NP_001129512
RefSeq Peptide - NP_001136037
RefSeq Peptide - NP_079087
swissprot - C9J323
swissprot - F5GXA3
swissprot - F5H047
swissprot - Q8N684
swissprot - F5H2K8
swissprot - F5H5B7
swissprot - F5H669
swissprot - F5H6A8
swissprot - F5H6M0
swissprot - F5H6P5
swissprot - J3QT54
swissprot - F5H1W4
swissprot - C9J286
swissprot - C9JM38
Ensembl - ENSG00000149532
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000039014Gallus gallus
 ENSGALG00000040962Gallus gallus
 Cpsf7ENSMUSG00000034820Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CPSF6 / Q16630 / cleavage and polyadenylation specific factor 6ENSG0000011160547


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR034770  Cleavage and polyadenylation specificity factor subunit 7
 IPR034772  CPSF6/7 family
 IPR034773  CPSF7, RNA recognition motif
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0031124 mRNA 3"-end processing TAS
 biological_processGO:0051262 protein tetramerization IDA
 biological_processGO:0051290 protein heterotetramerization IDA
 biological_processGO:0098789 pre-mRNA cleavage required for polyadenylation IMP
 biological_processGO:1990120 messenger ribonucleoprotein complex assembly IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005847 mRNA cleavage and polyadenylation specificity factor complex IDA
 cellular_componentGO:0005849 mRNA cleavage factor complex IEA
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
mRNA Splicing - Major Pathway
mRNA 3-end processing
Processing of Intronless Pre-mRNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000167005 NUDT21 / O43809 / nudix hydrolase 21  / complex
 ENSG00000165494 PCF11 / O94913 / PCF11 cleavage and polyadenylation factor subunit  / complex
 ENSG00000172409 CLP1 / Q92989 / cleavage and polyadenylation factor I subunit 1  / complex






 

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