ENSG00000165494


Homo sapiens

Features
Gene ID: ENSG00000165494
  
Biological name :PCF11
  
Synonyms : O94913 / PCF11 / PCF11 cleavage and polyadenylation factor subunit
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q14.1
Gene start: 83156988
Gene end: 83187451
  
Corresponding Affymetrix probe sets: 203378_at (Human Genome U133 Plus 2.0 Array)   227622_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000298281
Ensembl peptide - ENSP00000437076
Ensembl peptide - ENSP00000436806
Ensembl peptide - ENSP00000434540
Ensembl peptide - ENSP00000431567
NCBI entrez gene - 51585     See in Manteia.
OMIM - 608876
RefSeq - XM_017017918
RefSeq - NM_015885
RefSeq - XM_005274048
RefSeq - XM_005274049
RefSeq Peptide - NP_056969
swissprot - E9PQF9
swissprot - O94913
swissprot - E9PNY7
swissprot - E9PKN0
swissprot - E9PQ01
Ensembl - ENSG00000165494
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pcf11ENSDARG00000044625Danio rerio
 ENSGALG00000017249Gallus gallus
 Pcf11ENSMUSG00000041328Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006569  CID domain
 IPR006903  RNA polymerase II-binding domain
 IPR008942  ENTH/VHS


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006369 termination of RNA polymerase II transcription IBA
 biological_processGO:0006378 mRNA polyadenylation IBA
 biological_processGO:0006379 mRNA cleavage NAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0031124 mRNA 3"-end processing TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005849 mRNA cleavage factor complex IBA
 molecular_functionGO:0000993 RNA polymerase II core binding IBA
 molecular_functionGO:0003729 mRNA binding IBA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
RNA polymerase II transcribes snRNA genes
mRNA Splicing - Major Pathway
mRNA 3-end processing
Processing of Intronless Pre-mRNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000172409 CLP1 / Q92989 / cleavage and polyadenylation factor I subunit 1  / complex
 ENSG00000167005 NUDT21 / O43809 / nudix hydrolase 21  / complex
 ENSG00000149532 CPSF7 / Q8N684 / cleavage and polyadenylation specific factor 7  / complex






 

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