ENSG00000111671


Homo sapiens

Features
Gene ID: ENSG00000111671
  
Biological name :SPSB2
  
Synonyms : Q99619 / splA/ryanodine receptor domain and SOCS box containing 2 / SPSB2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p13.31
Gene start: 6870935
Gene end: 6889358
  
Corresponding Affymetrix probe sets: 223580_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000431037
Ensembl peptide - ENSP00000428338
Ensembl peptide - ENSP00000428458
Ensembl peptide - ENSP00000430872
NCBI entrez gene - 84727     See in Manteia.
OMIM - 611658
RefSeq - NM_001146316
RefSeq - NM_001319670
RefSeq - NM_032641
RefSeq Peptide - NP_001139788
RefSeq Peptide - NP_001306599
RefSeq Peptide - NP_116030
swissprot - Q99619
swissprot - E5RIC2
Ensembl - ENSG00000111671
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch1073-228j22.2ENSDARG00000088985Danio rerio
 Spsb2ENSMUSG00000038451Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SPSB4 / Q96A44 / splA/ryanodine receptor domain and SOCS box containing 4ENSG0000017509352
SPSB1 / Q96BD6 / splA/ryanodine receptor domain and SOCS box containing 1ENSG0000017162151
FBXO45 / P0C2W1 / F-box protein 45ENSG0000017401332


Protein motifs (from Interpro)
Interpro ID Name
 IPR001496  SOCS box domain
 IPR001870  B30.2/SPRY domain
 IPR003877  SPRY domain
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR036036  SOCS box-like domain superfamily
 IPR037340  SSB2, SOCS box domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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