ENSG00000175093


Homo sapiens

Features
Gene ID: ENSG00000175093
  
Biological name :SPSB4
  
Synonyms : Q96A44 / splA/ryanodine receptor domain and SOCS box containing 4 / SPSB4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q23
Gene start: 141051402
Gene end: 141148611
  
Corresponding Affymetrix probe sets: 229929_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000311609
Ensembl peptide - ENSP00000422034
NCBI entrez gene - 92369     See in Manteia.
OMIM - 611660
RefSeq - NM_080862
RefSeq Peptide - NP_543138
swissprot - Q96A44
swissprot - H0Y8T2
Ensembl - ENSG00000175093
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spsb4aENSDARG00000016084Danio rerio
 SPSB4ENSGALG00000032053Gallus gallus
 Spsb4ENSMUSG00000046997Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SPSB1 / Q96BD6 / splA/ryanodine receptor domain and SOCS box containing 1ENSG0000017162175
SPSB2 / Q99619 / splA/ryanodine receptor domain and SOCS box containing 2ENSG0000011167150
FBXO45 / P0C2W1 / F-box protein 45ENSG0000017401332


Protein motifs (from Interpro)
Interpro ID Name
 IPR001496  SOCS box domain
 IPR001870  B30.2/SPRY domain
 IPR003877  SPRY domain
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR036036  SOCS box-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr