ENSG00000171621


Homo sapiens

Features
Gene ID: ENSG00000171621
  
Biological name :SPSB1
  
Synonyms : Q96BD6 / splA/ryanodine receptor domain and SOCS box containing 1 / SPSB1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.22
Gene start: 9292880
Gene end: 9369532
  
Corresponding Affymetrix probe sets: 219677_at (Human Genome U133 Plus 2.0 Array)   226075_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000350573
Ensembl peptide - ENSP00000409235
Ensembl peptide - ENSP00000366616
Ensembl peptide - ENSP00000330221
NCBI entrez gene - 80176     See in Manteia.
OMIM - 611657
RefSeq - NM_025106
RefSeq Peptide - NP_079382
swissprot - A2A276
swissprot - A0A024R4G8
swissprot - Q96BD6
Ensembl - ENSG00000171621
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spsb1ENSDARG00000056515Danio rerio
 SPSB1ENSGALG00000002506Gallus gallus
 Spsb1ENSMUSG00000039911Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SPSB4 / Q96A44 / splA/ryanodine receptor domain and SOCS box containing 4ENSG0000017509375
SPSB2 / Q99619 / splA/ryanodine receptor domain and SOCS box containing 2ENSG0000011167149
FBXO45 / P0C2W1 / F-box protein 45ENSG0000017401329


Protein motifs (from Interpro)
Interpro ID Name
 IPR001496  SOCS box domain
 IPR001870  B30.2/SPRY domain
 IPR003877  SPRY domain
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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