ENSG00000174013


Homo sapiens

Features
Gene ID: ENSG00000174013
  
Biological name :FBXO45
  
Synonyms : F-box protein 45 / FBXO45 / P0C2W1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q29
Gene start: 196568611
Gene end: 196589059
  
Corresponding Affymetrix probe sets: 225099_at (Human Genome U133 Plus 2.0 Array)   225100_at (Human Genome U133 Plus 2.0 Array)   242294_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000310332
Ensembl peptide - ENSP00000389868
NCBI entrez gene - 200933     See in Manteia.
OMIM - 609112
RefSeq - NM_001105573
RefSeq Peptide - NP_001099043
swissprot - C9JLC0
swissprot - P0C2W1
Ensembl - ENSG00000174013
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxo45ENSDARG00000071492Danio rerio
 FBXO45ENSGALG00000037281Gallus gallus
 Fbxo45ENSMUSG00000035764Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SPSB4 / Q96A44 / splA/ryanodine receptor domain and SOCS box containing 4ENSG0000017509331
SPSB2 / Q99619 / splA/ryanodine receptor domain and SOCS box containing 2ENSG0000011167130
SPSB1 / Q96BD6 / splA/ryanodine receptor domain and SOCS box containing 1ENSG0000017162127


Protein motifs (from Interpro)
Interpro ID Name
 IPR001810  F-box domain
 IPR001870  B30.2/SPRY domain
 IPR003877  SPRY domain
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR035784  Fbxo45, SPRY domain
 IPR036047  F-box-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0006974 cellular response to DNA damage stimulus IDA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0016567 protein ubiquitination ISS
 biological_processGO:0021799 cerebral cortex radially oriented cell migration IEA
 biological_processGO:0021800 cerebral cortex tangential migration IEA
 biological_processGO:0021957 corticospinal tract morphogenesis IEA
 biological_processGO:0021960 anterior commissure morphogenesis IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0060384 innervation IEA
 biological_processGO:0060386 synapse assembly involved in innervation IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0042734 presynaptic membrane IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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