ENSG00000111707


Homo sapiens

Features
Gene ID: ENSG00000111707
  
Biological name :SUDS3
  
Synonyms : Q9H7L9 / SDS3 homolog, SIN3A corepressor complex component / SUDS3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q24.23
Gene start: 118376380
Gene end: 118418031
  
Corresponding Affymetrix probe sets: 224974_at (Human Genome U133 Plus 2.0 Array)   233841_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000443988
NCBI entrez gene - 64426     See in Manteia.
OMIM - 608250
RefSeq - XM_017019820
RefSeq - NM_022491
RefSeq - XM_017019818
RefSeq - XM_017019819
RefSeq - XM_011538671
RefSeq - XM_017019817
RefSeq Peptide - NP_071936
swissprot - Q9H7L9
Ensembl - ENSG00000111707
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 suds3ENSDARG00000073737Danio rerio
 SUDS3ENSGALG00000007393Gallus gallus
 Suds3ENSMUSG00000066900Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013907  Sds3-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0016575 histone deacetylation IDA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0021762 substantia nigra development HEP
 biological_processGO:0043065 positive regulation of apoptotic process IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016580 Sin3 complex ISS
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0070822 Sin3-type complex IBA
 molecular_functionGO:0004407 histone deacetylase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0042826 histone deacetylase binding IBA


Pathways (from Reactome)
Pathway description
HDACs deacetylate histones
NoRC negatively regulates rRNA expression
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000223443 Q6R6M4 / USP17L2 / ubiquitin specific peptidase 17-like family member 2  / complex






 

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