ENSG00000111790


Homo sapiens

Features
Gene ID: ENSG00000111790
  
Biological name :FGFR1OP2
  
Synonyms : FGFR1 oncogene partner 2 / FGFR1OP2 / Q9NVK5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p11.23
Gene start: 26938383
Gene end: 26966650
  
Corresponding Affymetrix probe sets: 1556282_at (Human Genome U133 Plus 2.0 Array)   1556283_s_at (Human Genome U133 Plus 2.0 Array)   223262_s_at (Human Genome U133 Plus 2.0 Array)   223263_s_at (Human Genome U133 Plus 2.0 Array)   233898_s_at (Human Genome U133 Plus 2.0 Array)   236808_at (Human Genome U133 Plus 2.0 Array)   243619_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000229395
Ensembl peptide - ENSP00000323763
Ensembl peptide - ENSP00000437556
Ensembl peptide - ENSP00000441144
NCBI entrez gene - 26127     See in Manteia.
OMIM - 608858
RefSeq - NM_001171887
RefSeq - NM_001171888
RefSeq - NM_015633
RefSeq Peptide - NP_001165358
RefSeq Peptide - NP_001165359
RefSeq Peptide - NP_056448
swissprot - Q9NVK5
swissprot - F5GX47
Ensembl - ENSG00000111790
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q7T338ENSDARG00000009657Danio rerio
 Q5ZKJ4ENSGALG00000014084Gallus gallus
 Q9CRA9ENSMUSG00000040242Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SIKE1 / Q9BRV8 / suppressor of IKBKE 1ENSG0000005272342


Protein motifs (from Interpro)
Interpro ID Name
 IPR008555  SIKE family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009611 response to wounding IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0042060 wound healing IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
Signaling by cytosolic FGFR1 fusion mutants
Signaling by FGFR1 in disease


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000126561 P42229 / STAT5A / signal transducer and activator of transcription 5A  / reaction
 ENSG00000173757 P51692 / STAT5B / signal transducer and activator of transcription 5B  / reaction
 ENSG00000111790 Q9NVK5 / FGFR1OP2 / FGFR1 oncogene partner 2  / complex






 

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contact: otassy@igbmc.fr