ENSG00000112659


Homo sapiens

Features
Gene ID: ENSG00000112659
  
Biological name :CUL9
  
Synonyms : CUL9 / cullin 9 / Q8IWT3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p21.1
Gene start: 43182175
Gene end: 43224587
  
Corresponding Affymetrix probe sets: 213204_at (Human Genome U133 Plus 2.0 Array)   236392_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000425649
Ensembl peptide - ENSP00000252050
Ensembl peptide - ENSP00000361730
Ensembl peptide - ENSP00000421116
NCBI entrez gene - 23113     See in Manteia.
OMIM - 607489
RefSeq - XM_017010590
RefSeq - XM_011514426
RefSeq - XM_011514427
RefSeq - XM_011514428
RefSeq - XM_011514429
RefSeq - XM_017010589
RefSeq - NM_015089
RefSeq - XM_011514422
RefSeq - XM_011514423
RefSeq - XM_011514424
RefSeq - XM_011514425
RefSeq Peptide - NP_055904
swissprot - H0Y8H9
swissprot - H0YA00
swissprot - E9PEZ1
swissprot - Q8IWT3
Ensembl - ENSG00000112659
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Cul9ENSMUSG00000040327Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CUL7 / Q14999 / cullin 7ENSG0000004409041
ZZEF1 / O43149 / zinc finger ZZ-type and EF-hand domain containing 1ENSG0000007475516


Protein motifs (from Interpro)
Interpro ID Name
 IPR001373  Cullin, N-terminal
 IPR001841  Zinc finger, RING-type
 IPR002867  IBR domain
 IPR004939  APC10/DOC domain
 IPR008979  Galactose-binding-like domain superfamily
 IPR011989  Armadillo-like helical
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR014722  Ribosomal protein L2, domain 2
 IPR016024  Armadillo-type fold
 IPR016157  Cullin, conserved site
 IPR016158  Cullin homology domain
 IPR017907  Zinc finger, RING-type, conserved site
 IPR019559  Cullin protein, neddylation domain
 IPR021097  CPH domain
 IPR031222  Cullin-9
 IPR036317  Cullin homology domain superfamily
 IPR036388  Winged helix-like DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0007088 regulation of mitotic nuclear division IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0031461 cullin-RING ubiquitin ligase complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100387 RBX1 / P62877 / ring-box 1  / complex
 ENSG00000129559 NEDD8 / Q15843 / neural precursor cell expressed, developmentally down-regulated 8  / reaction / complex
 ENSG00000130725 UBE2M / P61081 / ubiquitin conjugating enzyme E2 M  / reaction / complex
 ENSG00000044090 CUL7 / Q14999 / cullin 7  / complex / reaction
 ENSG00000124006 OBSL1 / O75147 / obscurin like 1  / reaction / complex
 ENSG00000169515 CCDC8 / Q9H0W5 / coiled-coil domain containing 8  / complex / reaction






 

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