ENSG00000114416


Homo sapiens

Features
Gene ID: ENSG00000114416
  
Biological name :FXR1
  
Synonyms : FMR1 autosomal homolog 1 / FXR1 / P51114
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q26.33
Gene start: 180868141
Gene end: 180982753
  
Corresponding Affymetrix probe sets: 201635_s_at (Human Genome U133 Plus 2.0 Array)   201636_at (Human Genome U133 Plus 2.0 Array)   201637_s_at (Human Genome U133 Plus 2.0 Array)   229519_at (Human Genome U133 Plus 2.0 Array)   230201_at (Human Genome U133 Plus 2.0 Array)   235960_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417125
Ensembl peptide - ENSP00000388828
Ensembl peptide - ENSP00000417513
Ensembl peptide - ENSP00000420643
Ensembl peptide - ENSP00000420515
Ensembl peptide - ENSP00000419933
Ensembl peptide - ENSP00000419793
Ensembl peptide - ENSP00000419047
Ensembl peptide - ENSP00000418724
Ensembl peptide - ENSP00000418097
Ensembl peptide - ENSP00000418027
Ensembl peptide - ENSP00000307633
Ensembl peptide - ENSP00000350170
NCBI entrez gene - 8087     See in Manteia.
OMIM - 600819
RefSeq - XM_017007301
RefSeq - NM_001013438
RefSeq - NM_001013439
RefSeq - NM_005087
RefSeq - XM_005247813
RefSeq - XM_005247814
RefSeq - XM_005247815
RefSeq - XM_005247816
RefSeq - XM_006713775
RefSeq - XM_017007298
RefSeq - XM_017007299
RefSeq - XM_017007300
RefSeq Peptide - NP_001013456
RefSeq Peptide - NP_005078
RefSeq Peptide - NP_001013457
swissprot - C9JZE0
swissprot - C9JYQ6
swissprot - C9JY20
swissprot - C9JAJ4
swissprot - C9J5B4
swissprot - C9IZ22
swissprot - H7C4S4
swissprot - B4DXZ6
swissprot - P51114
swissprot - E9PFF5
swissprot - E7EU85
Ensembl - ENSG00000114416
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fxr1ENSDARG00000022968Danio rerio
 FXR1ENSGALG00000008864Gallus gallus
 Fxr1ENSMUSG00000027680Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FXR2 / P51116 / FMR1 autosomal homolog 2ENSG0000012924564
FMR1 / Q06787 / fragile X mental retardation 1ENSG0000010208153


Protein motifs (from Interpro)
Interpro ID Name
 IPR004087  K Homology domain
 IPR004088  K Homology domain, type 1
 IPR008395  Agenet-like domain
 IPR022034  Fragile X-related 1 protein, C-terminal core
 IPR032172  Fragile X-related 1 protein, C-terminal region 1
 IPR032177  Fragile X-related 1 protein, C-terminal region 3
 IPR036612  K Homology domain, type 1 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007517 muscle organ development IEA
 biological_processGO:0017148 negative regulation of translation IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:2000637 positive regulation of gene silencing by miRNA IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus TAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005844 polysome IBA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0035770 ribonucleoprotein granule IEA
 cellular_componentGO:0043034 costamere IEA
 cellular_componentGO:0043197 dendritic spine IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0002151 G-quadruplex RNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IBA
 molecular_functionGO:0003730 mRNA 3"-UTR binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0033592 RNA strand annealing activity IDA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
Signaling by BRAF and RAF fusions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000114416 FXR1 / P51114 / FMR1 autosomal homolog 1  / complex






 

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