ENSG00000115694


Homo sapiens

Features
Gene ID: ENSG00000115694
  
Biological name :STK25
  
Synonyms : O00506 / serine/threonine kinase 25 / STK25
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q37.3
Gene start: 241492674
Gene end: 241509730
  
Corresponding Affymetrix probe sets: 201314_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000395104
Ensembl peptide - ENSP00000385687
Ensembl peptide - ENSP00000399212
Ensembl peptide - ENSP00000446008
Ensembl peptide - ENSP00000444886
Ensembl peptide - ENSP00000417020
Ensembl peptide - ENSP00000414191
Ensembl peptide - ENSP00000412617
Ensembl peptide - ENSP00000406208
Ensembl peptide - ENSP00000404960
Ensembl peptide - ENSP00000404552
Ensembl peptide - ENSP00000404469
Ensembl peptide - ENSP00000403866
Ensembl peptide - ENSP00000403607
Ensembl peptide - ENSP00000401114
Ensembl peptide - ENSP00000325748
Ensembl peptide - ENSP00000384162
Ensembl peptide - ENSP00000384444
Ensembl peptide - ENSP00000385541
NCBI entrez gene - 10494     See in Manteia.
OMIM - 602255
RefSeq - XM_017003171
RefSeq - NM_001271977
RefSeq - NM_001271978
RefSeq - NM_001271979
RefSeq - NM_001271980
RefSeq - NM_001282305
RefSeq - NM_001282306
RefSeq - NM_001282307
RefSeq - NM_001282308
RefSeq - NM_006374
RefSeq - XM_011510493
RefSeq - XM_011510494
RefSeq - XM_011510495
RefSeq - XM_011510496
RefSeq - XM_017003168
RefSeq - XM_017003169
RefSeq - XM_017003170
RefSeq Peptide - NP_001269235
RefSeq Peptide - NP_001269236
RefSeq Peptide - NP_001269237
RefSeq Peptide - NP_006365
RefSeq Peptide - NP_001258906
RefSeq Peptide - NP_001258907
RefSeq Peptide - NP_001258908
RefSeq Peptide - NP_001258909
RefSeq Peptide - NP_001269234
swissprot - C9K0M6
swissprot - C9JN58
swissprot - C9JJV0
swissprot - C9JIH8
swissprot - C9JFA1
swissprot - C9JDH9
swissprot - C9JCC0
swissprot - C9J8E8
swissprot - C9J6L2
swissprot - C9J232
swissprot - O00506
swissprot - A0A024R4B2
swissprot - A0A0S2Z4Y2
swissprot - H7C279
swissprot - E7EM58
Ensembl - ENSG00000115694
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stk25aENSDARG00000002210Danio rerio
 stk25bENSDARG00000039022Danio rerio
 STK25ENSGALG00000037739Gallus gallus
 Stk25ENSMUSG00000026277Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STK24 / Q9Y6E0 / serine/threonine kinase 24ENSG0000010257273
STK26 / Q9P289 / serine/threonine kinase 26ENSG0000013460267
STK3 / Q13188 / serine/threonine kinase 3ENSG0000010437542
STK4 / Q13043 / serine/threonine kinase 4ENSG0000010110941


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR035060  Serine/threonine kinase 25, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000185 activation of MAPKKK activity IEA
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006979 response to oxidative stress TAS
 biological_processGO:0007163 establishment or maintenance of cell polarity IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade IDA
 biological_processGO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide IGI
 biological_processGO:0042542 response to hydrogen peroxide IDA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0048812 neuron projection morphogenesis IBA
 biological_processGO:0050772 positive regulation of axonogenesis IEA
 biological_processGO:0051645 Golgi localization IDA
 biological_processGO:0051683 establishment of Golgi localization IMP
 biological_processGO:0090168 Golgi reassembly IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity TAS
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008349 MAP kinase kinase kinase kinase activity IBA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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