ENSG00000102572


Homo sapiens

Features
Gene ID: ENSG00000102572
  
Biological name :STK24
  
Synonyms : Q9Y6E0 / serine/threonine kinase 24 / STK24
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q32.2
Gene start: 98445185
Gene end: 98577940
  
Corresponding Affymetrix probe sets: 1562425_at (Human Genome U133 Plus 2.0 Array)   1562426_a_at (Human Genome U133 Plus 2.0 Array)   208854_s_at (Human Genome U133 Plus 2.0 Array)   208855_s_at (Human Genome U133 Plus 2.0 Array)   215188_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000402810
Ensembl peptide - ENSP00000402764
Ensembl peptide - ENSP00000442539
Ensembl peptide - ENSP00000365730
Ensembl peptide - ENSP00000365737
Ensembl peptide - ENSP00000380651
NCBI entrez gene - 8428     See in Manteia.
OMIM - 604984
RefSeq - XM_017020795
RefSeq - NM_001032296
RefSeq - NM_001286649
RefSeq - NM_003576
RefSeq - XM_005254079
RefSeq - XM_017020794
RefSeq Peptide - NP_001273578
RefSeq Peptide - NP_003567
RefSeq Peptide - NP_001027467
swissprot - Q5JV99
swissprot - H0Y630
swissprot - Q5U0E6
swissprot - Q9Y6E0
swissprot - B4DR80
swissprot - Q5JV98
Ensembl - ENSG00000102572
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stk24aENSDARG00000100955Danio rerio
 stk24bENSDARG00000023878Danio rerio
 STK24ENSGALG00000016885Gallus gallus
 Stk24ENSMUSG00000063410Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STK25 / O00506 / serine/threonine kinase 25ENSG0000011569470
STK26 / Q9P289 / serine/threonine kinase 26ENSG0000013460268
STK3 / Q13188 / serine/threonine kinase 3ENSG0000010437542
STK4 / Q13043 / serine/threonine kinase 4ENSG0000010110940


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000185 activation of MAPKKK activity IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress IMP
 biological_processGO:0009267 cellular response to starvation IMP
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030336 negative regulation of cell migration IMP
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0042542 response to hydrogen peroxide IDA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0046777 protein autophosphorylation IMP
 biological_processGO:0048679 regulation of axon regeneration IMP
 biological_processGO:0048812 neuron projection morphogenesis IBA
 biological_processGO:0097194 execution phase of apoptosis IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005794 Golgi apparatus TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008349 MAP kinase kinase kinase kinase activity IBA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Apoptotic cleavage of cellular proteins
Apoptotic execution phase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000164305 CASP3 / P42574 / caspase 3  / reaction
 ENSG00000165806 CASP7 / P55210 / caspase 7  / reaction






 

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