ENSG00000134602


Homo sapiens

Features
Gene ID: ENSG00000134602
  
Biological name :STK26
  
Synonyms : Q9P289 / serine/threonine kinase 26 / STK26
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q26.2
Gene start: 132023265
Gene end: 132075943
  
Corresponding Affymetrix probe sets: 218499_at (Human Genome U133 Plus 2.0 Array)   224407_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000346755
Ensembl peptide - ENSP00000377868
Ensembl peptide - ENSP00000418753
Ensembl peptide - ENSP00000419702
Ensembl peptide - ENSP00000377867
NCBI entrez gene - 51765     See in Manteia.
OMIM - 300547
RefSeq - XM_011531350
RefSeq - NM_001042452
RefSeq - NM_001042453
RefSeq - NM_016542
RefSeq - XM_011531349
RefSeq Peptide - NP_001035918
RefSeq Peptide - NP_057626
RefSeq Peptide - NP_001035917
swissprot - Q8NBY1
swissprot - Q9P289
swissprot - B4E0Y9
Ensembl - ENSG00000134602
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stk26ENSDARG00000060390Danio rerio
 STK26ENSGALG00000006049Gallus gallus
 Stk26ENSMUSG00000031112Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STK24 / Q9Y6E0 / serine/threonine kinase 24ENSG0000010257272
STK25 / O00506 / serine/threonine kinase 25ENSG0000011569469
STK4 / Q13043 / serine/threonine kinase 4ENSG0000010110942
STK3 / Q13188 / serine/threonine kinase 3ENSG0000010437541


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR035056  MST4, kinase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000185 activation of MAPKKK activity IEA
 biological_processGO:0006468 protein phosphorylation IMP
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0009267 cellular response to starvation IMP
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030033 microvillus assembly IDA
 biological_processGO:0030336 negative regulation of cell migration IMP
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0042542 response to hydrogen peroxide IDA
 biological_processGO:0042981 regulation of apoptotic process IDA
 biological_processGO:0046777 protein autophosphorylation IMP
 biological_processGO:0048812 neuron projection morphogenesis IBA
 biological_processGO:0097194 execution phase of apoptosis TAS
 biological_processGO:1903205 regulation of hydrogen peroxide-induced cell death IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005798 Golgi-associated vesicle IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0012506 vesicle membrane TAS
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016324 apical plasma membrane IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071944 cell periphery IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IDA
 molecular_functionGO:0004672 protein kinase activity IMP
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0008349 MAP kinase kinase kinase kinase activity IBA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Apoptotic cleavage of cellular proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000164305 CASP3 / P42574 / caspase 3  / reaction






 

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