ENSMUSG00000031112


Mus musculus

Features
Gene ID: ENSMUSG00000031112
  
Biological name :Stk26
  
Synonyms : Q99JT2 / serine/threonine kinase 26 / Stk26
  
Possible biological names infered from orthology : Q9P289
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: A5
Gene start: 50841047
Gene end: 50893097
  
Corresponding Affymetrix probe sets: 10599581 (MoGene1.0st)   1419032_at (Mouse Genome 430 2.0 Array)   1419033_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000110537
Ensembl peptide - ENSMUSP00000033444
NCBI entrez gene - 70415     See in Manteia.
MGI - MGI:1917665
RefSeq - XM_017318618
RefSeq - NM_001313744
RefSeq - NM_133729
RefSeq Peptide - NP_001300673
RefSeq Peptide - NP_598490
swissprot - A2AD84
swissprot - A2AD85
swissprot - Q99JT2
Ensembl - ENSMUSG00000031112
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stk26ENSDARG00000060390Danio rerio
 STK26ENSGALG00000006049Gallus gallus
 STK26ENSG00000134602Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Stk24 / Q99KH8 / serine/threonine kinase 24 / Q9Y6E0*ENSMUSG0000006341074
Stk25 / Q9Z2W1 / Serine/threonine-protein kinase 25 / O00506* / serine/threonine kinase 25*ENSMUSG0000002627769
Stk3 / Q9JI10 / Mus musculus serine/threonine kinase 3 (Stk3), transcript variant 2, mRNA. / Q13188* / serine/threonine kinase 3*ENSMUSG0000002232941
Stk4 / Q9JI11 / serine/threonine kinase 4 / Q13043*ENSMUSG0000001820941


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR035056  MST4, kinase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000185 activation of MAPKKK activity IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0009267 cellular response to starvation ISS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030033 microvillus assembly IEA
 biological_processGO:0030336 negative regulation of cell migration ISS
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0042542 response to hydrogen peroxide ISO
 biological_processGO:0042981 regulation of apoptotic process ISS
 biological_processGO:0046777 protein autophosphorylation ISS
 biological_processGO:0048812 neuron projection morphogenesis IBA
 biological_processGO:1903205 regulation of hydrogen peroxide-induced cell death ISO
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005798 Golgi-associated vesicle ISO
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0071944 cell periphery IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding ISO
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008349 MAP kinase kinase kinase kinase activity IBA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Apoptotic cleavage of cellular proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031628 Casp3 / P70677 / Caspase-3 Caspase-3 subunit p17 Caspase-3 subunit p12 / P42574* / caspase 3*  / reaction






 

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