ENSG00000117226


Homo sapiens

Features
Gene ID: ENSG00000117226
  
Biological name :GBP3
  
Synonyms : GBP3 / guanylate binding protein 3 / Q9H0R5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p22.2
Gene start: 89006666
Gene end: 89022894
  
Corresponding Affymetrix probe sets: 223434_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000456449
Ensembl peptide - ENSP00000455156
Ensembl peptide - ENSP00000455317
Ensembl peptide - ENSP00000235878
Ensembl peptide - ENSP00000359512
Ensembl peptide - ENSP00000415087
Ensembl peptide - ENSP00000437168
Ensembl peptide - ENSP00000454978
NCBI entrez gene - 2635     See in Manteia.
OMIM - 600413
RefSeq - XM_017001014
RefSeq - NM_001319179
RefSeq - NM_001319180
RefSeq - NM_001319181
RefSeq - NM_018284
RefSeq - XM_005270743
RefSeq - XM_006710574
RefSeq - XM_011541233
RefSeq - XM_011541234
RefSeq - XM_017001013
RefSeq Peptide - NP_060754
RefSeq Peptide - NP_001306110
RefSeq Peptide - NP_001306109
RefSeq Peptide - NP_001306108
swissprot - H3BPH2
swissprot - H3BRX6
swissprot - Q5T8M0
swissprot - Q9H0R5
swissprot - F6SPX6
swissprot - F6X827
swissprot - H3BNS1
swissprot - H3BP53
Ensembl - ENSG00000117226
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01068208.1ENSDARG00000112675Danio rerio
 CABZ01068209.1ENSDARG00000110616Danio rerio
 gbp1ENSDARG00000038668Danio rerio
 gbp2ENSDARG00000038669Danio rerio
 gbp4ENSDARG00000068857Danio rerio
 si:ch211-209n20.1ENSDARG00000099382Danio rerio
 si:dkeyp-30d6.2ENSDARG00000103564Danio rerio
 unm_sa911ENSDARG00000034063Danio rerio
 zmp:0000000527ENSDARG00000005627Danio rerio
 ENSGALG00000000720Gallus gallus
 GBPENSGALG00000026152Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GBP1 / P32455 / guanylate binding protein 1ENSG0000011722887
GBP2 / P32456 / guanylate binding protein 2ENSG0000016264574
GBP5 / Q96PP8 / guanylate binding protein 5ENSG0000015445167
GBP7 / Q8N8V2 / guanylate binding protein 7ENSG0000021351255
GBP4 / Q96PP9 / guanylate binding protein 4ENSG0000016265453
GBP6 / Q6ZN66 / guanylate binding protein family member 6ENSG0000018334751


Protein motifs (from Interpro)
Interpro ID Name
 IPR003191  Guanylate-binding protein/Atlastin, C-terminal
 IPR015894  Guanylate-binding protein, N-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030386  GB1/RHD3-type guanine nucleotide-binding (G) domain
 IPR036543  Guanylate-binding protein, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0051607 defense response to virus IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Interferon gamma signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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