ENSG00000183347


Homo sapiens

Features
Gene ID: ENSG00000183347
  
Biological name :GBP6
  
Synonyms : GBP6 / guanylate binding protein family member 6 / Q6ZN66
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p22.2
Gene start: 89364058
Gene end: 89386461
  
Corresponding Affymetrix probe sets: 1559606_at (Human Genome U133 Plus 2.0 Array)   1559607_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359485
NCBI entrez gene - 163351     See in Manteia.
OMIM - 612467
RefSeq - XM_011540835
RefSeq - NM_001320257
RefSeq - NM_198460
RefSeq Peptide - NP_940862
RefSeq Peptide - NP_001307186
swissprot - Q6ZN66
Ensembl - ENSG00000183347
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01068208.1ENSDARG00000112675Danio rerio
 CABZ01068209.1ENSDARG00000110616Danio rerio
 gbp1ENSDARG00000038668Danio rerio
 gbp2ENSDARG00000038669Danio rerio
 gbp4ENSDARG00000068857Danio rerio
 si:ch211-209n20.1ENSDARG00000099382Danio rerio
 si:dkeyp-30d6.2ENSDARG00000103564Danio rerio
 unm_sa911ENSDARG00000034063Danio rerio
 zmp:0000000527ENSDARG00000005627Danio rerio
 ENSGALG00000000720Gallus gallus
 GBPENSGALG00000026152Gallus gallus
 Gbp10ENSMUSG00000105096Mus musculus
 Gbp11ENSMUSG00000092021Mus musculus
 Gbp4ENSMUSG00000079363Mus musculus
 Gbp6ENSMUSG00000104713Mus musculus
 Gbp8ENSMUSG00000034438Mus musculus
 Gbp9ENSMUSG00000029298Mus musculus
 Gm43302ENSMUSG00000079362Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GBP4 / Q96PP9 / guanylate binding protein 4ENSG0000016265470
GBP7 / Q8N8V2 / guanylate binding protein 7ENSG0000021351269
GBP1 / P32455 / guanylate binding protein 1ENSG0000011722849
GBP2 / P32456 / guanylate binding protein 2ENSG0000016264549
GBP3 / Q9H0R5 / guanylate binding protein 3ENSG0000011722648
GBP5 / Q96PP8 / guanylate binding protein 5ENSG0000015445147


Protein motifs (from Interpro)
Interpro ID Name
 IPR003191  Guanylate-binding protein/Atlastin, C-terminal
 IPR015894  Guanylate-binding protein, N-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030386  GB1/RHD3-type guanine nucleotide-binding (G) domain
 IPR036543  Guanylate-binding protein, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response ISS
 biological_processGO:0042742 defense response to bacterium ISS
 biological_processGO:0071346 cellular response to interferon-gamma ISS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Interferon gamma signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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