ENSG00000162645


Homo sapiens

Features
Gene ID: ENSG00000162645
  
Biological name :GBP2
  
Synonyms : GBP2 / guanylate binding protein 2 / P32456
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p22.2
Gene start: 89106132
Gene end: 89150456
  
Corresponding Affymetrix probe sets: 202748_at (Human Genome U133 Plus 2.0 Array)   242907_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000434282
Ensembl peptide - ENSP00000359497
NCBI entrez gene - 2634     See in Manteia.
OMIM - 600412
RefSeq - NM_004120
RefSeq Peptide - NP_004111
swissprot - P32456
Ensembl - ENSG00000162645
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01068208.1ENSDARG00000112675Danio rerio
 CABZ01068209.1ENSDARG00000110616Danio rerio
 gbp1ENSDARG00000038668Danio rerio
 gbp2ENSDARG00000038669Danio rerio
 gbp4ENSDARG00000068857Danio rerio
 si:ch211-209n20.1ENSDARG00000099382Danio rerio
 si:dkeyp-30d6.2ENSDARG00000103564Danio rerio
 unm_sa911ENSDARG00000034063Danio rerio
 zmp:0000000527ENSDARG00000005627Danio rerio
 ENSGALG00000000720Gallus gallus
 GBPENSGALG00000026152Gallus gallus
 Gbp2ENSMUSG00000028270Mus musculus
 Gbp2bENSMUSG00000040264Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GBP1 / P32455 / guanylate binding protein 1ENSG0000011722876
GBP3 / Q9H0R5 / guanylate binding protein 3ENSG0000011722675
GBP5 / Q96PP8 / guanylate binding protein 5ENSG0000015445164
GBP7 / Q8N8V2 / guanylate binding protein 7ENSG0000021351255
GBP6 / Q6ZN66 / guanylate binding protein family member 6ENSG0000018334753
GBP4 / Q96PP9 / guanylate binding protein 4ENSG0000016265453


Protein motifs (from Interpro)
Interpro ID Name
 IPR003191  Guanylate-binding protein/Atlastin, C-terminal
 IPR015894  Guanylate-binding protein, N-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030386  GB1/RHD3-type guanine nucleotide-binding (G) domain
 IPR036543  Guanylate-binding protein, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response TAS
 biological_processGO:0060333 interferon-gamma-mediated signaling pathway TAS
 biological_processGO:0060337 type I interferon signaling pathway TAS
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding TAS
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Interferon gamma signaling
Interferon alpha/beta signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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