ENSMUSG00000040264


Mus musculus

Features
Gene ID: ENSMUSG00000040264
  
Biological name :Gbp2b
  
Synonyms : Gbp2b
  
Possible biological names infered from orthology : GBP2 / guanylate binding protein 2 / P32456
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: H1
Gene start: 142594847
Gene end: 142619179
  
Corresponding Affymetrix probe sets: 10496555 (MoGene1.0st)   1420549_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029936
NCBI entrez gene - 14468     See in Manteia.
MGI - MGI:95666
RefSeq - NM_010259
RefSeq - XM_011240014
RefSeq Peptide - NP_034389
swissprot - A4UUI2
Ensembl - ENSMUSG00000040264
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01068208.1ENSDARG00000112675Danio rerio
 CABZ01068209.1ENSDARG00000110616Danio rerio
 gbp1ENSDARG00000038668Danio rerio
 gbp2ENSDARG00000038669Danio rerio
 gbp4ENSDARG00000068857Danio rerio
 si:ch211-209n20.1ENSDARG00000099382Danio rerio
 si:dkeyp-30d6.2ENSDARG00000103564Danio rerio
 unm_sa911ENSDARG00000034063Danio rerio
 zmp:0000000527ENSDARG00000005627Danio rerio
 ENSGALG00000000720Gallus gallus
 GBPENSGALG00000026152Gallus gallus
 GBP2ENSG00000162645Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gbp2 / Q9Z0E6 / Guanylate-binding protein 2 / P32456*ENSMUSG0000002827076
Gbp5 / Q8CFB4 / Guanylate-binding protein 5 / Q96PP8*ENSMUSG0000010550454
Gbp3 / Q61107 / Mus musculus guanylate binding protein 3 (Gbp3), transcript variant 4, mRNA. / GBP4* / GBP7* / Q96PP9* / Q8N8V2* / guanylate binding protein 4* / guanylate binding protein 7*ENSMUSG0000002826851
Gbp7 / GBP4* / Q8N8V2* / Q96PP9* / guanylate binding protein 4* / guanylate binding protein 7*ENSMUSG0000004025351
Gm43302 / GBP6* / Q6ZN66* / guanylate binding protein family member 6*ENSMUSG0000007936250
Gbp6 / Q6ZN66* / guanylate binding protein family member 6*ENSMUSG0000010471350
Gbp10 / GBP6* / Q6ZN66* / guanylate binding protein family member 6*ENSMUSG0000010509649
Gbp9 / GBP6* / Q6ZN66* / guanylate binding protein family member 6*ENSMUSG0000002929848
Gbp4 / Mus musculus guanylate binding protein 4 (Gbp4), transcript variant 6, mRNA. / GBP6* / Q6ZN66* / guanylate binding protein family member 6*ENSMUSG0000007936345
Gbp11 / Mus musculus guanylate binding protein 11 (Gbp11), transcript variant 1, mRNA. / GBP6* / Q6ZN66* / guanylate binding protein family member 6*ENSMUSG0000009202142
Gbp8 / GBP6* / Q6ZN66* / guanylate binding protein family member 6*ENSMUSG0000003443842


Protein motifs (from Interpro)
Interpro ID Name
 IPR003191  Guanylate-binding protein/Atlastin, C-terminal
 IPR015894  Guanylate-binding protein, N-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030386  GB1/RHD3-type guanine nucleotide-binding (G) domain
 IPR036543  Guanylate-binding protein, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001263 weight loss "progressive reduction of body weight below normal average for age" [J:45400]
Show

Allelic Composition: Cd247tm1Lov/Cd247tm1Lov
Genetic Background: B6.129S4-Cd247tm1Lov/J

 MP:0002412 increased susceptibility to bacterial infection "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cd247tm1Lov/Cd247tm1Lov
Genetic Background: B6.129S4-Cd247tm1Lov/J

 MP:0002451 abnormal macrophage physiology "abnormal function or response of the phagocytic leukocytes involved in innate immunity, early non-adaptive phases of host-defense, antigen presentation, and which act as effector cells in humoral and cell-mediated immunity" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cd247tm1Lov/Cd247tm1Lov
Genetic Background: B6.129S4-Cd247tm1Lov/J

 MP:0005036 diarrhea "abnormally frequent discharge of semi-solid or fluid fecal matter from the bowel" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cd247tm1Lov/Cd247tm1Lov
Genetic Background: B6.129S4-Cd247tm1Lov/J

 MP:0009788 increased susceptibility to bacterial infection induced morbidity/mortality "increased likelihood that an organism will display the expected moribund state caused by a bacterial invasion or from components of or toxins produced by bacteria" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cd247tm1Lov/Cd247tm1Lov
Genetic Background: B6.129S4-Cd247tm1Lov/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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