ENSG00000119231


Homo sapiens

Features
Gene ID: ENSG00000119231
  
Biological name :SENP5
  
Synonyms : Q96HI0 / SENP5 / SUMO1/sentrin specific peptidase 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q29
Gene start: 196867856
Gene end: 196934714
  
Corresponding Affymetrix probe sets: 213184_at (Human Genome U133 Plus 2.0 Array)   222110_at (Human Genome U133 Plus 2.0 Array)   57703_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000327197
Ensembl peptide - ENSP00000396927
Ensembl peptide - ENSP00000405663
Ensembl peptide - ENSP00000415227
Ensembl peptide - ENSP00000390231
NCBI entrez gene - 205564     See in Manteia.
OMIM - 612845
RefSeq - XM_017005870
RefSeq - NM_001308045
RefSeq - NM_152699
RefSeq - XM_005269310
RefSeq - XM_005269312
RefSeq - XM_011512544
RefSeq Peptide - NP_689912
RefSeq Peptide - NP_001294974
swissprot - H7C2F8
swissprot - H7C424
swissprot - Q96HI0
swissprot - C9JHT8
Ensembl - ENSG00000119231
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 senp5ENSDARG00000060646Danio rerio
 SENP5ENSGALG00000008545Gallus gallus
 Senp5ENSMUSG00000022772Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SENP3 / Q9H4L4 / SUMO1/sentrin/SMT3 specific peptidase 3ENSG0000016195626
SENP3-EIF4A1 / SENP3-EIF4A1 readthrough (NMD candidate)ENSG0000027795725
SENP1 / Q9P0U3 / SUMO1/sentrin specific peptidase 1ENSG0000007938720
SENP2 / Q9HC62 / SUMO1/sentrin/SMT3 specific peptidase 2ENSG0000016390417


Protein motifs (from Interpro)
Interpro ID Name
 IPR003653  Ulp1 protease family, C-terminal catalytic domain
 IPR033465  SENP5 peptidase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016925 protein sumoylation TAS
 biological_processGO:0016926 protein desumoylation IEA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0004175 endopeptidase activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016929 SUMO-specific protease activity IEA
 molecular_functionGO:0070139 SUMO-specific endopeptidase activity EXP


Pathways (from Reactome)
Pathway description
SUMO is proteolytically processed


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000184900 SUMO3 / P55854 / small ubiquitin-like modifier 3  / reaction
 ENSG00000188612 SUMO2 / P61956 / small ubiquitin-like modifier 2  / reaction
 ENSG00000116030 SUMO1 / P63165 / small ubiquitin-like modifier 1  / reaction






 

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