ENSG00000120756


Homo sapiens

Features
Gene ID: ENSG00000120756
  
Biological name :PLS1
  
Synonyms : plastin 1 / PLS1 / Q14651
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q23
Gene start: 142596387
Gene end: 142713664
  
Corresponding Affymetrix probe sets: 205190_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000387890
Ensembl peptide - ENSP00000419893
Ensembl peptide - ENSP00000419531
Ensembl peptide - ENSP00000419271
Ensembl peptide - ENSP00000418880
Ensembl peptide - ENSP00000418700
Ensembl peptide - ENSP00000417491
Ensembl peptide - ENSP00000417481
Ensembl peptide - ENSP00000417311
Ensembl peptide - ENSP00000336831
NCBI entrez gene - 5357     See in Manteia.
OMIM - 602734
RefSeq - XM_017006627
RefSeq - NM_001145319
RefSeq - NM_001172312
RefSeq - NM_002670
RefSeq - XM_006713660
RefSeq - XM_011512900
RefSeq - XM_011512901
RefSeq - XM_011512903
RefSeq - XM_017006626
RefSeq Peptide - NP_001165783
RefSeq Peptide - NP_002661
RefSeq Peptide - NP_001138791
swissprot - C9JAM3
swissprot - C9J359
swissprot - C9J0F3
swissprot - C9JVY2
swissprot - C9JYI1
swissprot - Q14651
swissprot - C9JU08
swissprot - C9JAM8
Ensembl - ENSG00000120756
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pls1ENSDARG00000039272Danio rerio
 PLS1ENSGALG00000002647Gallus gallus
 Pls1ENSMUSG00000049493Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PLS3 / P13797 / plastin 3ENSG0000010202475
LCP1 / P13796 / lymphocyte cytosolic protein 1ENSG0000013616773


Protein motifs (from Interpro)
Interpro ID Name
 IPR001589  Actinin-type actin-binding domain, conserved site
 IPR001715  Calponin homology domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site
 IPR030235  Plastin-1
 IPR036872  CH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001951 intestinal D-glucose absorption IEA
 biological_processGO:0032532 regulation of microvillus length IEA
 biological_processGO:0040018 positive regulation of multicellular organism growth IEA
 biological_processGO:0051017 actin filament bundle assembly IBA
 biological_processGO:0051639 actin filament network formation IBA
 biological_processGO:0051764 actin crosslink formation IBA
 biological_processGO:1902896 terminal web assembly IEA
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane ISS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005884 actin filament IBA
 cellular_componentGO:0005903 brush border ISS
 cellular_componentGO:0032432 actin filament bundle IBA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1990357 terminal web IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton TAS
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051015 actin filament binding TAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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