ENSG00000121741


Homo sapiens

Features
Gene ID: ENSG00000121741
  
Biological name :ZMYM2
  
Synonyms : Q9UBW7 / zinc finger MYM-type containing 2 / ZMYM2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: 1
Band: q12.11
Gene start: 19958670
Gene end: 20091829
  
Corresponding Affymetrix probe sets: 202778_s_at (Human Genome U133 Plus 2.0 Array)   210281_s_at (Human Genome U133 Plus 2.0 Array)   210282_at (Human Genome U133 Plus 2.0 Array)   226512_at (Human Genome U133 Plus 2.0 Array)   240642_at (Human Genome U133 Plus 2.0 Array)   242597_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000479904
Ensembl peptide - ENSP00000483904
Ensembl peptide - ENSP00000372324
Ensembl peptide - ENSP00000372327
NCBI entrez gene - 7750     See in Manteia.
RefSeq - XM_017020738
RefSeq - XM_011535216
RefSeq - XM_011535222
RefSeq - XM_011535223
RefSeq - XM_011535224
RefSeq - XM_017020728
RefSeq - XM_017020729
RefSeq - XM_017020731
RefSeq - XM_017020732
RefSeq - XM_017020733
RefSeq - XM_017020734
RefSeq - XM_017020735
RefSeq - XM_017020736
RefSeq - XM_017020737
RefSeq - NM_001190964
RefSeq - NM_001190965
RefSeq - NM_001353157
RefSeq - NM_001353159
RefSeq - NM_001353161
RefSeq - NM_001353162
RefSeq - NM_001353163
RefSeq - NM_001353164
RefSeq - NM_003453
RefSeq - NM_197968
RefSeq - XM_005266520
RefSeq Peptide - NP_001177894
RefSeq Peptide - NP_001340086
RefSeq Peptide - NP_001340088
RefSeq Peptide - NP_001340090
RefSeq Peptide - NP_001340091
RefSeq Peptide - NP_001340092
RefSeq Peptide - NP_001340093
RefSeq Peptide - NP_003444
RefSeq Peptide - NP_932072
RefSeq Peptide - NP_001177893
swissprot - A0A024RDS3
swissprot - A0A087X151
swissprot - Q9UBW7
Ensembl - ENSG00000121741
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zmym2ENSDARG00000027353Danio rerio
 ENSGALG00000017139Gallus gallus
 ENSGALG00000043421Gallus gallus
 Zmym2ENSMUSG00000021945Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ZMYM3 / Q14202 / zinc finger MYM-type containing 3ENSG0000014713036
ZMYM4 / Q5VZL5 / zinc finger MYM-type containing 4ENSG0000014646335
ZMYM6 / O95789 / zinc finger MYM-type containing 6ENSG0000016386721
ZMYM5 / Q9UJ78 / zinc finger MYM-type containing 5ENSG0000013295019
AC114490.2ENSG0000027174117
Q2TAL8 / QRICH1 / glutamine rich 1ENSG0000019821813


Protein motifs (from Interpro)
Interpro ID Name
 IPR010507  Zinc finger, MYM-type
 IPR011017  TRASH domain
 IPR021893  Protein of unknown function DUF3504


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007010 cytoskeleton organization IBA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0022604 regulation of cell morphogenesis IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016605 PML body IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding NAS
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Signaling by cytosolic FGFR1 fusion mutants
Signaling by FGFR1 in disease


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000121741 ZMYM2 / Q9UBW7 / zinc finger MYM-type containing 2  / complex
 ENSG00000126561 P42229 / STAT5A / signal transducer and activator of transcription 5A  / reaction
 ENSG00000173757 P51692 / STAT5B / signal transducer and activator of transcription 5B  / reaction






 

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