ENSG00000121933


Homo sapiens

Features
Gene ID: ENSG00000121933
  
Biological name :TMIGD3
  
Synonyms : P0DMS9 / TMIGD3 / transmembrane and immunoglobulin domain containing 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p13.2
Gene start: 111483348
Gene end: 111563962
  
Corresponding Affymetrix probe sets: 223660_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000488683
Ensembl peptide - ENSP00000358730
Ensembl peptide - ENSP00000358731
Ensembl peptide - ENSP00000398770
NCBI entrez gene - 57413     See in Manteia.
RefSeq - NM_001302680
RefSeq - NM_001081976
RefSeq - NM_020683
RefSeq Peptide - NP_001075445
RefSeq Peptide - NP_001289609
RefSeq Peptide - NP_065734
swissprot - Q5QNY8
swissprot - P0DMS9
swissprot - A0A0J9YY46
Ensembl - ENSG00000121933
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR847944.1ENSDARG00000026246Danio rerio
 CR847944.2ENSDARG00000059899Danio rerio
 si:ch211-233f11.5ENSDARG00000044061Danio rerio
 ADORA3ENSGALG00000001462Gallus gallus
 G3X8R9ENSMUSG00000074344Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADORA3 / P0DMS8 / adenosine A3 receptorENSG0000028260838
P29274 / ADORA2A / adenosine A2a receptorENSG0000012827124
ADORA1 / P30542 / adenosine A1 receptorENSG0000016348524
P29275 / ADORA2B / adenosine A2b receptorENSG0000017042522
GPR119 / Q8TDV5 / G protein-coupled receptor 119ENSG0000014726212


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000466  Adenosine A3 receptor
 IPR013783  Immunoglobulin-like fold
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007190 activation of adenylate cyclase activity TAS
 biological_processGO:0008016 regulation of heart contraction TAS
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0009611 response to wounding TAS
 biological_processGO:0030336 negative regulation of cell migration IMP
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IMP
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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