ENSG00000124602


Homo sapiens

Features
Gene ID: ENSG00000124602
  
Biological name :UNC5CL
  
Synonyms : Q8IV45 / UNC5CL / unc-5 family C-terminal like
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.1
Gene start: 41026911
Gene end: 41039217
  
Corresponding Affymetrix probe sets: 231008_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000244565
Ensembl peptide - ENSP00000362258
NCBI entrez gene - 222643     See in Manteia.
OMIM - 617464
RefSeq - NM_173561
RefSeq Peptide - NP_775832
swissprot - Q8IV45
swissprot - H8YHX0
Ensembl - ENSG00000124602
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Unc5clENSMUSG00000043592Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
UNC5C / O95185 / unc-5 netrin receptor CENSG0000018216825
UNC5B / Q8IZJ1 / unc-5 netrin receptor BENSG0000010773125
UNC5D / Q6UXZ4 / unc-5 netrin receptor DENSG0000015668724
UNC5A / Q6ZN44 / unc-5 netrin receptor AENSG0000011376323


Protein motifs (from Interpro)
Interpro ID Name
 IPR000488  Death domain
 IPR000906  ZU5 domain
 IPR011029  Death-like domain superfamily
 IPR033772  UPA domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0038007 netrin-activated signaling pathway IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IDA
 biological_processGO:0046330 positive regulation of JNK cascade IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005042 netrin receptor activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008233 peptidase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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