ENSG00000156687


Homo sapiens

Features
Gene ID: ENSG00000156687
  
Biological name :UNC5D
  
Synonyms : Q6UXZ4 / UNC5D / unc-5 netrin receptor D
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: p12
Gene start: 35235457
Gene end: 35796550
  
Corresponding Affymetrix probe sets: 231325_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000392739
Ensembl peptide - ENSP00000385143
Ensembl peptide - ENSP00000394303
Ensembl peptide - ENSP00000412652
Ensembl peptide - ENSP00000397211
Ensembl peptide - ENSP00000287272
NCBI entrez gene - 137970     See in Manteia.
OMIM - 616466
RefSeq - XM_017013050
RefSeq - XM_011544404
RefSeq - XM_017013044
RefSeq - XM_017013045
RefSeq - XM_017013046
RefSeq - XM_017013047
RefSeq - XM_017013048
RefSeq - XM_017013049
RefSeq - NM_001322818
RefSeq - NM_080872
RefSeq - XM_011544400
RefSeq - XM_011544401
RefSeq - XM_011544402
RefSeq - XM_011544403
RefSeq Peptide - NP_001309747
RefSeq Peptide - NP_543148
swissprot - H7BXJ2
swissprot - E9PDS8
swissprot - C9J1I0
swissprot - Q6UXZ4
swissprot - C9J2B6
Ensembl - ENSG00000156687
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 unc5daENSDARG00000092722Danio rerio
 unc5dbENSDARG00000061541Danio rerio
 UNC5DENSGALG00000001608Gallus gallus
 Unc5dENSMUSG00000063626Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
UNC5B / Q8IZJ1 / unc-5 netrin receptor BENSG0000010773151
UNC5C / O95185 / unc-5 netrin receptor CENSG0000018216849
UNC5A / Q6ZN44 / unc-5 netrin receptor AENSG0000011376339
Q8IV45 / UNC5CL / unc-5 family C-terminal likeENSG0000012460213


Protein motifs (from Interpro)
Interpro ID Name
 IPR000488  Death domain
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR000906  ZU5 domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR011029  Death-like domain superfamily
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR033772  UPA domain
 IPR036179  Immunoglobulin-like domain superfamily
 IPR036383  Thrombospondin type-1 (TSP1) repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0021859 pyramidal neuron differentiation IEA
 biological_processGO:0038007 netrin-activated signaling pathway IEA
 biological_processGO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules IDA
 biological_processGO:2001222 regulation of neuron migration IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005042 netrin receptor activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Netrin mediated repulsion signals


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000065320 NTN1 / O95631 / netrin 1  / reaction / complex
 ENSG00000187323 DCC / P43146 / DCC netrin 1 receptor  / reaction / complex






 

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