ENSMUSG00000063626


Mus musculus

Features
Gene ID: ENSMUSG00000063626
  
Biological name :Unc5d
  
Synonyms : Q8K1S2 / Unc5d / unc-5 netrin receptor D
  
Possible biological names infered from orthology : Q6UXZ4
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: A2
Gene start: 28646717
Gene end: 29219636
  
Corresponding Affymetrix probe sets: 10577996 (MoGene1.0st)   10577999 (MoGene1.0st)   1440484_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000148236
Ensembl peptide - ENSMUSP00000128521
Ensembl peptide - ENSMUSP00000147306
Ensembl peptide - ENSMUSP00000147721
Ensembl peptide - ENSMUSP00000148043
NCBI entrez gene - 210801     See in Manteia.
MGI - MGI:2389364
RefSeq - XM_006509058
RefSeq - NM_153135
RefSeq - XM_006509049
RefSeq - XM_006509050
RefSeq - XM_006509051
RefSeq - XM_006509052
RefSeq - XM_006509053
RefSeq - XM_006509054
RefSeq - XM_006509055
RefSeq - XM_006509056
RefSeq - XM_006509057
RefSeq Peptide - NP_001334428
RefSeq Peptide - NP_001334429
RefSeq Peptide - NP_001334430
RefSeq Peptide - NP_694775
RefSeq Peptide - NP_001334427
swissprot - Q8K1S2
swissprot - B7ZMT2
swissprot - A6H5Z5
swissprot - A0A1B0GSR6
swissprot - C5IAW8
Ensembl - ENSMUSG00000063626
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 unc5daENSDARG00000092722Danio rerio
 unc5dbENSDARG00000061541Danio rerio
 UNC5DENSGALG00000001608Gallus gallus
 UNC5DENSG00000156687Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Unc5b / Q8K1S3 / unc-5 netrin receptor B / Q8IZJ1*ENSMUSG0000002009950
Unc5c / O08747 / unc-5 netrin receptor C / O95185*ENSMUSG0000005992149
Unc5a / Q8K1S4 / unc-5 netrin receptor A / Q6ZN44*ENSMUSG0000002587644
Unc5cl / unc-5 family C-terminal like / Q8IV45*ENSMUSG0000004359213


Protein motifs (from Interpro)
Interpro ID Name
 IPR000488  Death domain
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR000906  ZU5 domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR011029  Death-like domain superfamily
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR033772  UPA domain
 IPR036179  Immunoglobulin-like domain superfamily
 IPR036383  Thrombospondin type-1 (TSP1) repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007411 axon guidance IGI
 biological_processGO:0021859 pyramidal neuron differentiation IDA
 biological_processGO:0038007 netrin-activated signaling pathway IEA
 biological_processGO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules IEA
 biological_processGO:2001222 regulation of neuron migration IGI
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005042 netrin receptor activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003651 abnormal axon outgrowth "defect/abnormality in the ability of an axon to extend from a neuron cell body" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:96121]
Show

Allelic Composition: Flrt3tm2Kln/Flrt3tm3Kln,Tg(Pgk1-cre)1Lni/0
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * BALB/c * C57BL/6

 MP:0006009 abnormal neuronal migration "defective or impaired movement of immature neurons from germinal zones to specific positions where they will reside as they mature" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Flrt3tm2Kln/Flrt3tm3Kln,Tg(Pgk1-cre)1Lni/0
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * BALB/c * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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