ENSMUSG00000059921


Mus musculus

Features
Gene ID: ENSMUSG00000059921
  
Biological name :Unc5c
  
Synonyms : O08747 / Unc5c / unc-5 netrin receptor C
  
Possible biological names infered from orthology : O95185
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: H1
Gene start: 141465216
Gene end: 141834924
  
Corresponding Affymetrix probe sets: 10496519 (MoGene1.0st)   1419592_at (Mouse Genome 430 2.0 Array)   1449522_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118212
Ensembl peptide - ENSMUSP00000074758
Ensembl peptide - ENSMUSP00000101843
Ensembl peptide - ENSMUSP00000117487
NCBI entrez gene - 22253     See in Manteia.
MGI - MGI:1095412
RefSeq - NM_009472
RefSeq - NM_001293561
RefSeq Peptide - NP_001280490
RefSeq Peptide - NP_033498
swissprot - Q3UQ08
swissprot - O08747
swissprot - E9PVI4
Ensembl - ENSMUSG00000059921
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch73-72b7.1ENSDARG00000099133Danio rerio
 unc5cENSDARG00000087341Danio rerio
 UNC5CENSGALG00000012219Gallus gallus
 UNC5CENSG00000182168Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Unc5b / Q8K1S3 / unc-5 netrin receptor B / Q8IZJ1*ENSMUSG0000002009963
Unc5a / Q8K1S4 / unc-5 netrin receptor A / Q6ZN44*ENSMUSG0000002587652
Unc5d / Q8K1S2 / unc-5 netrin receptor D / Q6UXZ4*ENSMUSG0000006362650
Unc5cl / unc-5 family C-terminal like / Q8IV45*ENSMUSG0000004359213


Protein motifs (from Interpro)
Interpro ID Name
 IPR000488  Death domain
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR000906  ZU5 domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR011029  Death-like domain superfamily
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR033772  UPA domain
 IPR036179  Immunoglobulin-like domain superfamily
 IPR036383  Thrombospondin type-1 (TSP1) repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007411 axon guidance IGI
 biological_processGO:0007420 brain development IMP
 biological_processGO:0030334 regulation of cell migration IMP
 biological_processGO:0033564 anterior/posterior axon guidance IMP
 biological_processGO:0038007 netrin-activated signaling pathway IEA
 biological_processGO:0043065 positive regulation of apoptotic process IMP
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0005042 netrin receptor activity IDA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: F11tm1Gjb/F11tm1Gjb,Proctm1Fjc/Proctm1Fjc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000776 abnormal inferior colliculus "dysmorphology or disorganization of the paired inferior eminence of the mesencephalic tectum that is involved in preliminary visual processing, and control of eye movements" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Lattm1.1Lov/Lattm1.1Lov
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: involves: C57BL/6J * SJL/J

 MP:0000777 increased size of inferior colliculus "enlargement of the paired inferior eminence of the mesencephalic tectum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:57538]
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Allelic Composition: Unc5crcm/Unc5crcm
Genetic Background: C57BL/6J-Unc5crcm

 MP:0000849 abnormal cerebellum morphology "any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Unc5crcm/Unc5crcm
Genetic Background: C57BL/6J-Unc5crcm

 MP:0000852 small cerebellum "reduced size of cerebellum" [MGI:CLS, J:17203, J:67524]
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Allelic Composition: Lattm1.1Lov/Lattm1.1Lov
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: involves: C57BL/6J * SJL/J

Allelic Composition: Unc5crcmTg(Tert)5Hwl/Unc5crcmTg(Tert)5Hwl
Genetic Background: involves: FVB/N

Allelic Composition: Unc5crcm/Unc5crcm
Genetic Background: C57BL/6J-Unc5crcm

 MP:0000854 abnormal cerebellum development "malformed or incomplete differentiation of the part of the metencephalon that lies dorsal to the pons and medulla behind the brain stem and controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Lattm1.1Lov/Lattm1.1Lov
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: involves: C57BL/6J * SJL/J

Allelic Composition: Unc5crcmTg(Tert)5Hwl/Unc5crcmTg(Tert)5Hwl
Genetic Background: involves: FVB/N

 MP:0000872 abnormal external granule cell layer "malformation of the transient layer of the cerebellar cortex which is composed of the dividing and migrating granule cells" [tc:Teresa Chu , Mouse Genome Informatics Curator]
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Allelic Composition: Lattm1.1Lov/Lattm1.1Lov
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: involves: C57BL/6J * SJL/J

 MP:0000875 abnormal cerebellar Purkinje cell layer "any malformation or absence of the cell layer that lies just underneath the molecular layer of the cerebellar cortex; it contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer, and candelabrum interneurons are vertically oriented between the Purkinje cells" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Lattm1.1Lov/Lattm1.1Lov
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: involves: C57BL/6J * SJL/J

Allelic Composition: Unc5crcm/Unc5crcm
Genetic Background: C57BL/6J-Unc5crcm

 MP:0000877 abnormal Purkinje cell "any structural anomaly of the neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex; these inhibitory neurons provide the output of the cerebellar cortex through axons that project into the white matter, and extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells" [J:46140, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Lattm1.1Lov/Lattm1.1Lov
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000885 ectopic Purkinje cell "Purkinje cell body resides in places other than the Purkinje cell layer in the cerebellum" [MGI:tc, J:60896]
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Allelic Composition: Lattm1.1Lov/Lattm1.1Lov
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: involves: C57BL/6J * SJL/J

Allelic Composition: Unc5crcm/Unc5crcm
Genetic Background: C57BL/6J-Unc5crcm

 MP:0000886 abnormal cerebellar granule layer "any malformation or absence of the innermost cortical layer of the cerebellum; contains densly packed small neurons, mostly granule cells with some Golgi cells are found at the outer border" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Lattm1.1Lov/Lattm1.1Lov
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Unc5crcm/Unc5crcm
Genetic Background: C57BL/6J-Unc5crcm

 MP:0000889 abnormal cerebellar molecular layer "any malformation or absence of the outermost layer of the cerebral cortex that contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857]
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Allelic Composition: Lattm1.1Lov/Lattm1.1Lov
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000899 abnormal colliculi "malformed inferior and superior colliculus" [J:50311]
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Allelic Composition: Unc5crcmTg(Tert)5Hwl/Unc5crcmTg(Tert)5Hwl
Genetic Background: involves: FVB/N

 MP:0001052 abnormal muscle innervation "malfomation or misprojection of sensory or motor nerves to targets in muscle" [J:75958]
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Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: involves: C57BL/6J * SJL/J

 MP:0001063 abnormal trochlear nerve morphology "any malformation or misprojection of the 4th cranial nerve, which normally carries the motor innervation of the superior oblique muscles of the eye " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: involves: C57BL/6J * SJL/J

Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: B6.Cg-Unc5crcmTg(Ucp)1.23Kz

 MP:0001078 abnormal phrenic nerve "malformed or misprojection of motor and sensory neuron axons to the diaphragm and other tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
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Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: B6.Cg-Unc5crcmTg(Ucp)1.23Kz

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Apctm2Tno/Apc+
Genetic Background: Not Specified

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Apctm2Tno/Apc+
Genetic Background: Not Specified

 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
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Allelic Composition: Lattm1.1Lov/Lattm1.1Lov
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: involves: C57BL/6J * SJL/J

Allelic Composition: Unc5crcmTg(Tert)5Hwl/Unc5crcmTg(Tert)5Hwl
Genetic Background: involves: FVB/N

Allelic Composition: Unc5crcm/Unc5crcm
Genetic Background: C57BL/6J-Unc5crcm

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
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Allelic Composition: Unc5crcmTg(Tert)5Hwl/Unc5crcmTg(Tert)5Hwl
Genetic Background: involves: FVB/N

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
Show

Allelic Composition: Lattm1.1Lov/Lattm1.1Lov
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Unc5crcmTg(Tert)5Hwl/Unc5crcmTg(Tert)5Hwl
Genetic Background: involves: FVB/N

Allelic Composition: Unc5crcm/Unc5crcm
Genetic Background: C57BL/6J-Unc5crcm

 MP:0001410 head bobbing "compulsive up and down movement of the head" [J:17123]
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Allelic Composition: Unc5crcm/Unc5crcm
Genetic Background: C57BL/6J-Unc5crcm

 MP:0001504 abnormal posture "atypical position of the limbs or carriage of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984]
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Allelic Composition: F11tm1Gjb/F11tm1Gjb,Proctm1Fjc/Proctm1Fjc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Lattm1.1Lov/Lattm1.1Lov
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Unc5crcm/Unc5crcm
Genetic Background: C57BL/6J-Unc5crcm

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Unc5crcm/Unc5crcm
Genetic Background: C57BL/6J-Unc5crcm

 MP:0002762 ectopic granule cells "granule cell body resides in a place other than the external or internal granule layer of the cerebellum" [J:4978]
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Allelic Composition: Lattm1.1Lov/Lattm1.1Lov
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: involves: C57BL/6J * SJL/J

Allelic Composition: Unc5crcm/Unc5crcm
Genetic Background: C57BL/6J-Unc5crcm

 MP:0002878 abnormal corticospinal tract "anomaly in the structure or function of the fibers that arise from the cells within the cerebral cortex, pass through the medullary pyramid, and descend in the spinal cord" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: involves: C57BL/6J * SJL/J

 MP:0002961 abnormal axon guidance "defect in the signaling mechanisms that allow precise navigation and connections of axonal growth cones to effector tissues " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Dcctm1Wbg/Dcc+,Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: involves: 129X1/SvJ * C57BL/6J * SJL/J

Allelic Composition: Dcctm1Wbg/Dcc+,Unc5crcmTg(Ucp)1.23Kz/Unc5c+
Genetic Background: involves: 129X1/SvJ * C57BL/6J * SJL/J

 MP:0005334 abnormal fat pad "malformed or aberrant size of the encapsulated adipose tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Unc5crcmTg(Tert)5Hwl/Unc5crcmTg(Tert)5Hwl
Genetic Background: involves: FVB/N

 MP:0006009 abnormal neuronal migration "defective or impaired movement of immature neurons from germinal zones to specific positions where they will reside as they mature" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Lattm1.1Lov/Lattm1.1Lov
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0006097 abnormal cerebellar lobule formation "anomaly in the formation of the lobes of the cerebellum" [smb:Susan M Bello, Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:65410]
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Allelic Composition: Lattm1.1Lov/Lattm1.1Lov
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: involves: C57BL/6J * SJL/J

 MP:0006319 abnormal epididymal fat pad "any structural anomaly of the encapsulated adipose tissue associated with the epididymis" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Unc5crcmTg(Tert)5Hwl/Unc5crcmTg(Tert)5Hwl
Genetic Background: involves: FVB/N

 MP:0009677 abnormal spinal cord dorsal column morphology "any structural anomaly of the wedge-shaped fiber bundle of white matter in the dorsomedial side of the spinal cord that is made up of the fasciculus gracilis and fasciculus cuneatus; it is part of the ascending posterior column-medial lemniscus pathway that is important for well-localized fine touch and conscious proprioception" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN-10:0940780577 "Goldberg, S, Clinical Neuroanatomy Made Ridiculously Simple, 3rd edition"]
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Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: involves: C57BL/6J * SJL/J

 MP:0009681 abnormal pyramidal decussation morphology "any structural anomaly of the bundles of pyramidal fibers that intercross obliquely over the midline at the lower border region of the medulla oblongata" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: involves: C57BL/6J * SJL/J

 MP:0009719 reduced cerebellar foliation "the cerebellar lobules are reduced in size or number" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Lattm1.1Lov/Lattm1.1Lov
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: involves: C57BL/6J * SJL/J

 MP:0009956 abnormal cerebellar layer morphology "any structural anomaly of the laminar structure of the cerebellar cortex comprising the gray matter of the cerebellum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Unc5crcm/Unc5crcm
Genetic Background: C57BL/6J-Unc5crcm

 MP:0009957 abnormal cerebellum vermis lobule morphology "any structural anomaly of the region of a cerebellar lobule that resides in the central section of the cerebellum between the two hemispheres; in humans, vermis lobule regions may be nearly continuous with the cerebellar hemisphere lobules dorsally but are separated by deeper longitudinal fissues in the ventral regions; in mammals, the vermis portion of the cerebellum has a foliation pattern along the AP axis that is distinct from the lateral cerebellar hemispheres" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:17506688]
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Allelic Composition: Unc5crcm/Unc5crcm
Genetic Background: C57BL/6J-Unc5crcm

 MP:0009960 abnormal cerebellum anterior lobe morphology "any structural anomaly of the region of the cerebellum that is anterior to the primary fissure" [ISBN:0838580343 "Kandel ER, et al. Principles of Neural Science, 3rd edition"]
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Allelic Composition: Unc5crcm/Unc5crcm
Genetic Background: C57BL/6J-Unc5crcm

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: B6.Cg-Unc5crcmTg(Ucp)1.23Kz

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Unc5crcm/Unc5crcm
Genetic Background: C57BL/6J-Unc5crcm

 MP:0011939 increased food intake "increase in the total number of calories/food amount taken in over time when compared to the normal state" [MGI:csmith]
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Allelic Composition: Unc5crcmTg(Tert)5Hwl/Unc5crcmTg(Tert)5Hwl
Genetic Background: involves: FVB/N

 MP:0011941 increased fluid intake "increase in the total amount of fluid taken in over time when compared to the normal state" [MGI:csmith]
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Allelic Composition: Unc5crcmTg(Tert)5Hwl/Unc5crcmTg(Tert)5Hwl
Genetic Background: involves: FVB/N

 MP:0012055 abnormal phrenic nerve innervation pattern to diaphragm "any changes in the placement, morphology or number of the portion of phrenic nerve fibers providing motor supply to the diaphragm" [MGI:csmith]
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Allelic Composition: Unc5crcmTg(Ucp)1.23Kz/Unc5crcmTg(Ucp)1.23Kz
Genetic Background: B6.Cg-Unc5crcmTg(Ucp)1.23Kz

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000020902 Ntn1 / O09118 / Netrin-1 / O95631*  / complex
 ENSMUSG00000027646 Src / P05480 / Neuronal proto-onco tyrosine-protein kinase Src / P12931* / SRC proto-oncogene, non-receptor tyrosine kinase*  / reaction
 ENSMUSG00000060534 Dcc / P70211 / Netrin receptor DCC / P43146* / DCC netrin 1 receptor*  / complex
 ENSMUSG00000043733 P35235 / Ptpn11 / Tyrosine-protein phosphatase non-receptor type 11 / Q06124* / protein tyrosine phosphatase, non-receptor type 11*  / complex / reaction






 

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