ENSG00000125430


Homo sapiens

Features
Gene ID: ENSG00000125430
  
Biological name :HS3ST3B1
  
Synonyms : heparan sulfate-glucosamine 3-sulfotransferase 3B1 / HS3ST3B1 / Q9Y662
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: p12
Gene start: 14301083
Gene end: 14349404
  
Corresponding Affymetrix probe sets: 1561908_a_at (Human Genome U133 Plus 2.0 Array)   221062_at (Human Genome U133 Plus 2.0 Array)   227361_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000436078
Ensembl peptide - ENSP00000354213
NCBI entrez gene - 9953     See in Manteia.
OMIM - 604058
RefSeq - NM_006041
RefSeq Peptide - NP_006032
swissprot - Q9Y662
Ensembl - ENSG00000125430
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hs3st3b1aENSDARG00000099149Danio rerio
 hs3st3b1bENSDARG00000086645Danio rerio
 si:ch211-216b21.2ENSDARG00000060253Danio rerio
 ENSGALG00000001371Gallus gallus
 ENSGALG00000031058Gallus gallus
 Q8BKN6ENSMUSG00000047759Mus musculus
 Q9QZS6ENSMUSG00000070407Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9Y663 / HS3ST3A1 / heparan sulfate-glucosamine 3-sulfotransferase 3A1ENSG0000015397675
HS3ST4 / Q9Y661 / heparan sulfate-glucosamine 3-sulfotransferase 4ENSG0000018260158
HS3ST2 / Q9Y278 / heparan sulfate-glucosamine 3-sulfotransferase 2ENSG0000012225455
HS3ST6 / Q96QI5 / heparan sulfate-glucosamine 3-sulfotransferase 6ENSG0000016204054
HS3ST5 / Q8IZT8 / heparan sulfate-glucosamine 3-sulfotransferase 5ENSG0000024985335
HS3ST1 / O14792 / heparan sulfate-glucosamine 3-sulfotransferase 1ENSG0000000258730
NDST3 / O95803 / N-deacetylase and N-sulfotransferase 3ENSG0000016410028
NDST4 / Q9H3R1 / N-deacetylase and N-sulfotransferase 4ENSG0000013865328
NDST2 / P52849 / N-deacetylase and N-sulfotransferase 2ENSG0000016650728
NDST1 / P52848 / N-deacetylase and N-sulfotransferase 1ENSG0000007061427
AC022400.6 / bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform 2 ENSG0000027291623


Protein motifs (from Interpro)
Interpro ID Name
 IPR000863  Sulfotransferase domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR037359  Heparan sulfate sulfotransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006024 glycosaminoglycan biosynthetic process TAS
 biological_processGO:0015012 heparan sulfate proteoglycan biosynthetic process TAS
 biological_processGO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification TAS
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008146 sulfotransferase activity IEA
 molecular_functionGO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0033872 [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity IEA


Pathways (from Reactome)
Pathway description
HS-GAG biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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