ENSG00000002587


Homo sapiens

Features
Gene ID: ENSG00000002587
  
Biological name :HS3ST1
  
Synonyms : heparan sulfate-glucosamine 3-sulfotransferase 1 / HS3ST1 / O14792
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: p15.33
Gene start: 11393150
Gene end: 11429765
  
Corresponding Affymetrix probe sets: 205465_x_at (Human Genome U133 Plus 2.0 Array)   205466_s_at (Human Genome U133 Plus 2.0 Array)   213991_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000002596
Ensembl peptide - ENSP00000425673
Ensembl peptide - ENSP00000422629
NCBI entrez gene - 9957     See in Manteia.
OMIM - 603244
RefSeq - NM_005114
RefSeq - XM_011513913
RefSeq Peptide - NP_005105
swissprot - E9PDE3
swissprot - A0A024R9R4
swissprot - O14792
Ensembl - ENSG00000002587
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hs3st1l2ENSDARG00000035578Danio rerio
 HS3ST1ENSGALG00000014934Gallus gallus
 Hs3st1ENSMUSG00000051022Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HS3ST5 / Q8IZT8 / heparan sulfate-glucosamine 3-sulfotransferase 5ENSG0000024985349
HS3ST2 / Q9Y278 / heparan sulfate-glucosamine 3-sulfotransferase 2ENSG0000012225440
HS3ST4 / Q9Y661 / heparan sulfate-glucosamine 3-sulfotransferase 4ENSG0000018260140
Q9Y663 / HS3ST3A1 / heparan sulfate-glucosamine 3-sulfotransferase 3A1ENSG0000015397639
Q9Y662 / HS3ST3B1 / heparan sulfate-glucosamine 3-sulfotransferase 3B1ENSG0000012543038
HS3ST6 / Q96QI5 / heparan sulfate-glucosamine 3-sulfotransferase 6ENSG0000016204037
NDST4 / Q9H3R1 / N-deacetylase and N-sulfotransferase 4ENSG0000013865328
NDST2 / P52849 / N-deacetylase and N-sulfotransferase 2ENSG0000016650727
NDST3 / O95803 / N-deacetylase and N-sulfotransferase 3ENSG0000016410026
NDST1 / P52848 / N-deacetylase and N-sulfotransferase 1ENSG0000007061425
AC022400.6 / bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform 2 ENSG0000027291620


Protein motifs (from Interpro)
Interpro ID Name
 IPR000863  Sulfotransferase domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR037359  Heparan sulfate sulfotransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006024 glycosaminoglycan biosynthetic process TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005796 Golgi lumen TAS
 cellular_componentGO:0016021 integral component of membrane TAS
 molecular_functionGO:0008146 sulfotransferase activity IEA
 molecular_functionGO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity TAS
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
HS-GAG biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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