ENSMUSG00000051022


Mus musculus

Features
Gene ID: ENSMUSG00000051022
  
Biological name :Hs3st1
  
Synonyms : Heparan sulfate glucosamine 3-O-sulfotransferase 1 / Hs3st1 / O35310
  
Possible biological names infered from orthology : heparan sulfate-glucosamine 3-sulfotransferase 1 / O14792
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: B3
Gene start: 39613935
Gene end: 39755475
  
Corresponding Affymetrix probe sets: 10529732 (MoGene1.0st)   1423450_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113919
Ensembl peptide - ENSMUSP00000118060
Ensembl peptide - ENSMUSP00000114997
Ensembl peptide - ENSMUSP00000051055
NCBI entrez gene - 15476     See in Manteia.
MGI - MGI:1201606
RefSeq - NM_010474
RefSeq - XM_017320686
RefSeq Peptide - NP_034604
swissprot - D3YZM3
swissprot - O35310
swissprot - D3YUR4
Ensembl - ENSMUSG00000051022
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hs3st1l2ENSDARG00000035578Danio rerio
 HS3ST1ENSGALG00000014934Gallus gallus
 HS3ST1ENSG00000002587Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hs3st5 / Q8BSL4 / heparan sulfate (glucosamine) 3-O-sulfotransferase 5 / Q8IZT8* / heparan sulfate-glucosamine 3-sulfotransferase 5*ENSMUSG0000004449949
Hs3st4 / heparan sulfate-glucosamine 3-sulfotransferase 4 / Q9Y661*ENSMUSG0000007859141
Q8BKN6 / Hs3st3a1 / Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 / Q9Y662* / HS3ST3B1* / heparan sulfate-glucosamine 3-sulfotransferase 3B1*ENSMUSG0000004775940
Q9QZS6 / Hs3st3b1 / Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 / Q9Y662* / heparan sulfate-glucosamine 3-sulfotransferase 3B1*ENSMUSG0000007040739
Hs3st2 / Q673U1 / Heparan sulfate glucosamine 3-O-sulfotransferase 2 / Q9Y278* / heparan sulfate-glucosamine 3-sulfotransferase 2*ENSMUSG0000004632139
Hs3st6 / Q5GFD5 / Heparan sulfate glucosamine 3-O-sulfotransferase 6 / Q96QI5* / heparan sulfate-glucosamine 3-sulfotransferase 6*ENSMUSG0000003962838
Ndst4 / Q9EQW8 / Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 Heparan sulfate N-deacetylase 4 Heparan sulfate N-sulfotransferase 4 / Q9H3R1* / N-deacetylase and N-sulfotr...ENSMUSG0000002797128
Ndst3 / Q9EQH7 / N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 / O95803* / N-deacetylase and N-sulfotransferase 3*ENSMUSG0000002797728
Ndst2 / P52850 / N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 / P52849* / AC022400.6* / N-deacetylase and N-sulfotransferase 2* / bifunctional heparan sulfate N-deacetylase/N-s...ENSMUSG0000003930827
Ndst1 / Q3UHN9 / Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 Heparan sulfate N-deacetylase 1 Heparan sulfate N-sulfotransferase 1 / P52848* / N-deacetylase and N-sulfotr...ENSMUSG0000005400826


Protein motifs (from Interpro)
Interpro ID Name
 IPR000863  Sulfotransferase domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR037359  Heparan sulfate sulfotransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005796 Golgi lumen IEA
 molecular_functionGO:0008146 sulfotransferase activity IEA
 molecular_functionGO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
HS-GAG biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0009429 decreased embryo weight "reduced weight of an embryo compared to littermates or other controls (sensu Mus: up to E14, or the completion of organogenesis)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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