ENSG00000182601


Homo sapiens

Features
Gene ID: ENSG00000182601
  
Biological name :HS3ST4
  
Synonyms : heparan sulfate-glucosamine 3-sulfotransferase 4 / HS3ST4 / Q9Y661
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p12.1
Gene start: 25692026
Gene end: 26137688
  
Corresponding Affymetrix probe sets: 228206_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000330606
NCBI entrez gene - 9951     See in Manteia.
OMIM - 604059
RefSeq - NM_006040
RefSeq Peptide - NP_006031
swissprot - Q9Y661
Ensembl - ENSG00000182601
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hs3st4ENSDARG00000052648Danio rerio
 HS3ST4ENSGALG00000006290Gallus gallus
 Hs3st4ENSMUSG00000078591Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HS3ST2 / Q9Y278 / heparan sulfate-glucosamine 3-sulfotransferase 2ENSG0000012225451
Q9Y662 / HS3ST3B1 / heparan sulfate-glucosamine 3-sulfotransferase 3B1ENSG0000012543049
Q9Y663 / HS3ST3A1 / heparan sulfate-glucosamine 3-sulfotransferase 3A1ENSG0000015397649
HS3ST6 / Q96QI5 / heparan sulfate-glucosamine 3-sulfotransferase 6ENSG0000016204043
HS3ST5 / Q8IZT8 / heparan sulfate-glucosamine 3-sulfotransferase 5ENSG0000024985331
HS3ST1 / O14792 / heparan sulfate-glucosamine 3-sulfotransferase 1ENSG0000000258727
NDST3 / O95803 / N-deacetylase and N-sulfotransferase 3ENSG0000016410023
NDST1 / P52848 / N-deacetylase and N-sulfotransferase 1ENSG0000007061423
NDST4 / Q9H3R1 / N-deacetylase and N-sulfotransferase 4ENSG0000013865323
NDST2 / P52849 / N-deacetylase and N-sulfotransferase 2ENSG0000016650723
AC022400.6 / bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform 2 ENSG0000027291618


Protein motifs (from Interpro)
Interpro ID Name
 IPR000863  Sulfotransferase domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR037359  Heparan sulfate sulfotransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030201 heparan sulfate proteoglycan metabolic process NAS
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008146 sulfotransferase activity IEA
 molecular_functionGO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity NAS
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
HS-GAG biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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