ENSG00000126777


Homo sapiens

Features
Gene ID: ENSG00000126777
  
Biological name :KTN1
  
Synonyms : kinectin 1 / KTN1 / Q86UP2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q22.3
Gene start: 55559072
Gene end: 55701526
  
Corresponding Affymetrix probe sets: 200914_x_at (Human Genome U133 Plus 2.0 Array)   200915_x_at (Human Genome U133 Plus 2.0 Array)   214709_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000452445
Ensembl peptide - ENSP00000452337
Ensembl peptide - ENSP00000452459
Ensembl peptide - ENSP00000452576
Ensembl peptide - ENSP00000378719
Ensembl peptide - ENSP00000378720
Ensembl peptide - ENSP00000378722
Ensembl peptide - ENSP00000378725
Ensembl peptide - ENSP00000391964
Ensembl peptide - ENSP00000394992
Ensembl peptide - ENSP00000432149
Ensembl peptide - ENSP00000451139
Ensembl peptide - ENSP00000451641
Ensembl peptide - ENSP00000451698
Ensembl peptide - ENSP00000451876
Ensembl peptide - ENSP00000451878
Ensembl peptide - ENSP00000452073
Ensembl peptide - ENSP00000452205
NCBI entrez gene - 3895     See in Manteia.
OMIM - 600381
RefSeq - XM_017021286
RefSeq - NM_001271014
RefSeq - NM_004986
RefSeq - XM_006720138
RefSeq - XM_006720139
RefSeq - XM_006720140
RefSeq - XM_006720141
RefSeq - XM_011536751
RefSeq - XM_011536752
RefSeq - XM_011536753
RefSeq - XM_017021278
RefSeq - XM_017021279
RefSeq - XM_017021280
RefSeq - XM_017021281
RefSeq - XM_017021282
RefSeq - XM_017021283
RefSeq - XM_017021284
RefSeq - XM_017021285
RefSeq - NM_001079521
RefSeq - NM_001079522
RefSeq Peptide - NP_001257943
RefSeq Peptide - NP_004977
RefSeq Peptide - NP_001072989
RefSeq Peptide - NP_001072990
swissprot - G3V5G2
swissprot - G3V5P0
swissprot - G3V5Q0
swissprot - H0YJB7
swissprot - B7Z6P3
swissprot - H0YJV5
swissprot - H0YJZ8
swissprot - Q86UP2
swissprot - A0A024R663
swissprot - H0YJP2
swissprot - G3V475
swissprot - G3V4L8
swissprot - G3V4Y7
Ensembl - ENSG00000126777
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ktn1ENSDARG00000032802Danio rerio
 KTN1ENSGALG00000012137Gallus gallus
 Ktn1ENSMUSG00000021843Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RRBP1 / Q9P2E9 / ribosome binding protein 1ENSG0000012584422


Protein motifs (from Interpro)
Interpro ID Name
 IPR007794  Ribosome receptor lysine/proline rich
 IPR024854  Kinectin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0044267 cellular protein metabolic process TAS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019894 kinesin binding IEA
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
RHO GTPases activate KTN1
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000177105 RHOG / P84095 / ras homolog family member G  / complex / reaction
 ENSG00000126214 KLC1 / Q07866 / kinesin light chain 1  / reaction / complex
 ENSG00000136238 RAC1 / P63000 / Rac family small GTPase 1  / reaction / complex
 ENSG00000174996 KLC2 / Q9H0B6 / kinesin light chain 2  / complex / reaction
 ENSG00000067560 RHOA / P61586 / ras homolog family member A  / reaction / complex
 ENSG00000126777 KTN1 / Q86UP2 / kinectin 1  / complex
 ENSG00000070831 CDC42 / P60953 / cell division cycle 42  / complex / reaction
 ENSG00000155980 KIF5A / Q12840 / kinesin family member 5A  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr