ENSG00000127124


Homo sapiens

Features
Gene ID: ENSG00000127124
  
Biological name :HIVEP3
  
Synonyms : HIVEP3 / human immunodeficiency virus type I enhancer binding protein 3 / Q5T1R4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p34.2
Gene start: 41506365
Gene end: 42035925
  
Corresponding Affymetrix probe sets: 220042_x_at (Human Genome U133 Plus 2.0 Array)   232581_x_at (Human Genome U133 Plus 2.0 Array)   233884_at (Human Genome U133 Plus 2.0 Array)   235122_at (Human Genome U133 Plus 2.0 Array)   244764_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361664
Ensembl peptide - ENSP00000361665
Ensembl peptide - ENSP00000494598
NCBI entrez gene - 59269     See in Manteia.
OMIM - 606649
RefSeq - XM_017001994
RefSeq - NM_001127714
RefSeq - NM_024503
RefSeq - XM_011541884
RefSeq - XM_017001992
RefSeq - XM_017001993
RefSeq Peptide - NP_078779
RefSeq Peptide - NP_001121186
swissprot - Q5T1R4
Ensembl - ENSG00000127124
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hivep3aENSDARG00000075928Danio rerio
 hivep3bENSDARG00000037154Danio rerio
 HIVEP3ENSGALG00000027365Gallus gallus
 A2A884ENSMUSG00000028634Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HIVEP2 / P31629 / human immunodeficiency virus type I enhancer binding protein 2ENSG0000001081831
HIVEP1 / P15822 / human immunodeficiency virus type I enhancer binding protein 1ENSG0000009595131
Q5JPB2 / ZNF831 / zinc finger protein 831ENSG0000012420312


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR034729  Zinc finger CCHC HIVEP-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IBA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0035914 skeletal muscle cell differentiation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0043565 sequence-specific DNA binding IBA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of RUNX2 expression and activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000124813 RUNX2 / Q13950 / runt related transcription factor 2  / complex / reaction
 ENSG00000123124 WWP1 / Q9H0M0 / WW domain containing E3 ubiquitin protein ligase 1  / complex / reaction






 

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