ENSG00000131899


Homo sapiens

Features
Gene ID: ENSG00000131899
  
Biological name :LLGL1
  
Synonyms : LLGL1 / LLGL1, scribble cell polarity complex component / Q15334
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: p11.2
Gene start: 18225587
Gene end: 18244875
  
Corresponding Affymetrix probe sets: 206123_at (Human Genome U133 Plus 2.0 Array)   206124_s_at (Human Genome U133 Plus 2.0 Array)   227302_s_at (Human Genome U133 Plus 2.0 Array)   236594_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000480006
Ensembl peptide - ENSP00000321537
NCBI entrez gene - 3996     See in Manteia.
OMIM - 600966
RefSeq - XM_011523856
RefSeq - NM_004140
RefSeq - XM_011523853
RefSeq - XM_011523854
RefSeq - XM_011523855
RefSeq - XM_011523849
RefSeq - XM_011523850
RefSeq - XM_011523851
RefSeq - XM_011523852
RefSeq Peptide - NP_004131
swissprot - Q15334
swissprot - A0A087WW77
Ensembl - ENSG00000131899
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 llgl1ENSDARG00000009693Danio rerio
 LLGL1ENSGALG00000014408Gallus gallus
 Llgl1ENSMUSG00000020536Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LLGL2 / Q6P1M3 / LLGL2, scribble cell polarity complex componentENSG0000007335053
Q5T5C0 / STXBP5 / syntaxin binding protein 5ENSG0000016450627
Q9Y2K9 / STXBP5L / syntaxin binding protein 5 likeENSG0000014508726


Protein motifs (from Interpro)
Interpro ID Name
 IPR000664  Lethal(2) giant larvae protein
 IPR001680  WD40 repeat
 IPR013577  Lethal giant larvae homologue 2
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR019775  WD40 repeat, conserved site
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0006893 Golgi to plasma membrane transport ISS
 biological_processGO:0007409 axonogenesis ISS
 biological_processGO:0017157 regulation of exocytosis IBA
 biological_processGO:0030866 cortical actin cytoskeleton organization IDA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0050708 regulation of protein secretion IBA
 biological_processGO:0065003 protein-containing complex assembly IDA
 cellular_componentGO:0000137 Golgi cis cisterna ISS
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005856 cytoskeleton TAS
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0030864 cortical actin cytoskeleton IDA
 cellular_componentGO:0031901 early endosome membrane ISS
 cellular_componentGO:0032588 trans-Golgi network membrane ISS
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005198 structural molecule activity TAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017137 Rab GTPase binding IBA
 molecular_functionGO:0019901 protein kinase binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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