ENSG00000164506


Homo sapiens

Features
Gene ID: ENSG00000164506
  
Biological name :STXBP5
  
Synonyms : Q5T5C0 / STXBP5 / syntaxin binding protein 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q24.3
Gene start: 147204425
Gene end: 147390476
  
Corresponding Affymetrix probe sets: 226794_at (Human Genome U133 Plus 2.0 Array)   235227_at (Human Genome U133 Plus 2.0 Array)   243904_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000441479
Ensembl peptide - ENSP00000356451
Ensembl peptide - ENSP00000376112
Ensembl peptide - ENSP00000321826
Ensembl peptide - ENSP00000356445
Ensembl peptide - ENSP00000356450
NCBI entrez gene - 134957     See in Manteia.
OMIM - 604586
RefSeq - XM_017010268
RefSeq - NM_001127715
RefSeq - NM_139244
RefSeq - XM_006715339
RefSeq - XM_011535453
RefSeq - XM_017010267
RefSeq Peptide - NP_001121187
RefSeq Peptide - NP_640337
swissprot - Q5JRH0
swissprot - Q5T5C0
swissprot - H0Y332
swissprot - Q3B794
Ensembl - ENSG00000164506
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stxbp5aENSDARG00000002656Danio rerio
 stxbp5bENSDARG00000029234Danio rerio
 STXBP5ENSGALG00000012336Gallus gallus
 Q8K400ENSMUSG00000019790Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9Y2K9 / STXBP5L / syntaxin binding protein 5 likeENSG0000014508767
LLGL1 / Q15334 / LLGL1, scribble cell polarity complex componentENSG0000013189925
LLGL2 / Q6P1M3 / LLGL2, scribble cell polarity complex componentENSG0000007335025


Protein motifs (from Interpro)
Interpro ID Name
 IPR000664  Lethal(2) giant larvae protein
 IPR001388  Synaptobrevin
 IPR001680  WD40 repeat
 IPR013577  Lethal giant larvae homologue 2
 IPR013905  Lethal giant larvae (Lgl)-like, C-terminal domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0017157 regulation of exocytosis TAS
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0045921 positive regulation of exocytosis ISS
 biological_processGO:0050708 regulation of protein secretion IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0005892 acetylcholine-gated channel complex ISS
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017075 syntaxin-1 binding ISS
 molecular_functionGO:0017137 Rab GTPase binding IBA
 molecular_functionGO:0019905 syntaxin binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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