ENSG00000145087


Homo sapiens

Features
Gene ID: ENSG00000145087
  
Biological name :STXBP5L
  
Synonyms : Q9Y2K9 / STXBP5L / syntaxin binding protein 5 like
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q13.33
Gene start: 120908072
Gene end: 121424761
  
Corresponding Affymetrix probe sets: 1568896_at (Human Genome U133 Plus 2.0 Array)   215518_at (Human Genome U133 Plus 2.0 Array)   240236_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419404
Ensembl peptide - ENSP00000273666
Ensembl peptide - ENSP00000419627
Ensembl peptide - ENSP00000420666
Ensembl peptide - ENSP00000420642
Ensembl peptide - ENSP00000420287
Ensembl peptide - ENSP00000420167
Ensembl peptide - ENSP00000420019
NCBI entrez gene - 9515     See in Manteia.
OMIM - 609381
RefSeq - XM_017007535
RefSeq - NM_001308330
RefSeq - NM_001348343
RefSeq - NM_014980
RefSeq - XM_006713825
RefSeq - XM_011513328
RefSeq - XM_011513331
RefSeq - XM_011513333
RefSeq - XM_017007530
RefSeq - XM_017007531
RefSeq - XM_017007532
RefSeq - XM_017007533
RefSeq - XM_017007534
RefSeq Peptide - NP_055795
RefSeq Peptide - NP_001295259
RefSeq Peptide - NP_001335272
RefSeq Peptide - NP_001335273
RefSeq Peptide - NP_001335274
swissprot - E9PFI2
swissprot - C9JCY1
swissprot - Q9Y2K9
swissprot - C9K0E4
swissprot - C9JUZ7
swissprot - C9JQS3
swissprot - C9JPK3
Ensembl - ENSG00000145087
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5SQE2ENSDARG00000006383Danio rerio
 STXBP5LENSGALG00000032361Gallus gallus
 Q5DQR4ENSMUSG00000022829Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5T5C0 / STXBP5 / syntaxin binding protein 5ENSG0000016450665
LLGL2 / Q6P1M3 / LLGL2, scribble cell polarity complex componentENSG0000007335025
LLGL1 / Q15334 / LLGL1, scribble cell polarity complex componentENSG0000013189923


Protein motifs (from Interpro)
Interpro ID Name
 IPR000664  Lethal(2) giant larvae protein
 IPR001388  Synaptobrevin
 IPR001680  WD40 repeat
 IPR013577  Lethal giant larvae homologue 2
 IPR013905  Lethal giant larvae (Lgl)-like, C-terminal domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0017157 regulation of exocytosis IBA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0046676 negative regulation of insulin secretion IEA
 biological_processGO:0050708 regulation of protein secretion IBA
 biological_processGO:0050714 positive regulation of protein secretion IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017137 Rab GTPase binding IBA
 molecular_functionGO:0019905 syntaxin binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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