ENSG00000133247


Homo sapiens

Features
Gene ID: ENSG00000133247
  
Biological name :KMT5C
  
Synonyms : KMT5C / lysine methyltransferase 5C / Q86Y97
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.42
Gene start: 55339853
Gene end: 55348120
  
Corresponding Affymetrix probe sets: 1570058_at (Human Genome U133 Plus 2.0 Array)   224431_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000486397
Ensembl peptide - ENSP00000255613
Ensembl peptide - ENSP00000397296
Ensembl peptide - ENSP00000467499
NCBI entrez gene - 84787     See in Manteia.
OMIM - 613198
RefSeq - XM_017027388
RefSeq - NM_032701
RefSeq - XM_005259338
RefSeq - XM_006723442
RefSeq - XM_011527415
RefSeq Peptide - NP_116090
swissprot - Q86Y97
swissprot - A0A0D9SF94
Ensembl - ENSG00000133247
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kmt5cENSDARG00000075461Danio rerio
 Kmt5cENSMUSG00000059851Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KMT5B / Q4FZB7 / lysine methyltransferase 5BENSG0000011006644


Protein motifs (from Interpro)
Interpro ID Name
 IPR001214  SET domain
 IPR025790  Histone-lysine N-methyltransferase, Suvar4-20


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016571 histone methylation IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0034773 histone H4-K20 trimethylation IEA
 cellular_componentGO:0000780 condensed nuclear chromosome, centromeric region IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005720 nuclear heterochromatin IDA
 cellular_componentGO:0005721 pericentric heterochromatin IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity IEA
 molecular_functionGO:0042799 histone methyltransferase activity (H4-K20 specific) IEA


Pathways (from Reactome)
Pathway description
PKMTs methylate histone lysines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000276180 P62805 / HIST1H4I / histone cluster 1 H4 family member i  / reaction






 

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