ENSG00000134545


Homo sapiens

Features
Gene ID: ENSG00000134545
  
Biological name :KLRC1
  
Synonyms : killer cell lectin like receptor C1 / KLRC1 / P26715
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p13.2
Gene start: 10442264
Gene end: 10454685
  
Corresponding Affymetrix probe sets: 206785_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000442545
Ensembl peptide - ENSP00000438038
Ensembl peptide - ENSP00000441432
Ensembl peptide - ENSP00000256965
Ensembl peptide - ENSP00000352064
Ensembl peptide - ENSP00000385304
NCBI entrez gene - 3821     See in Manteia.
OMIM - 161555
RefSeq - NM_001304448
RefSeq - NM_002259
RefSeq - NM_007328
RefSeq - NM_213657
RefSeq - NM_213658
RefSeq Peptide - NP_998823
RefSeq Peptide - NP_002250
RefSeq Peptide - NP_015567
RefSeq Peptide - NP_998822
RefSeq Peptide - NP_001291377
swissprot - P26715
swissprot - H0YGB7
swissprot - F5GYZ0
Ensembl - ENSG00000134545
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Klrc1ENSMUSG00000030167Mus musculus
 Klrc2ENSMUSG00000052736Mus musculus
 Klrc3ENSMUSG00000033027Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLRC2 / P26717 / killer cell lectin like receptor C2ENSG0000020580976
AC068775.1ENSG0000025564170
KLRC3 / Q07444 / killer cell lectin like receptor C3ENSG0000020581070
KLRC4 / O43908 / killer cell lectin like receptor C4ENSG0000018354242
KLRC4-KLRK1 / KLRC4-KLRK1 readthroughENSG0000025581941
KLRD1 / Q13241 / killer cell lectin like receptor D1ENSG0000013453922
KLRK1 / P26718 / killer cell lectin like receptor K1ENSG0000021380917


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR033992  Natural killer cell receptor-like, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0050776 regulation of immune response TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IDA
 molecular_functionGO:0004888 transmembrane signaling receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0023024 MHC class I protein complex binding IPI
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000134539 KLRD1 / Q13241 / killer cell lectin like receptor D1  / complex / reaction
 ENSG00000166710 B2M / P61769 / beta-2-microglobulin  / reaction / complex






 

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