ENSG00000205809


Homo sapiens

Features
Gene ID: ENSG00000205809
  
Biological name :KLRC2
  
Synonyms : killer cell lectin like receptor C2 / KLRC2 / P26717
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p13.2
Gene start: 10426854
Gene end: 10442300
  
Corresponding Affymetrix probe sets: 206785_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000444754
Ensembl peptide - ENSP00000479152
Ensembl peptide - ENSP00000445240
Ensembl peptide - ENSP00000371326
Ensembl peptide - ENSP00000371327
Ensembl peptide - ENSP00000438983
NCBI entrez gene - 3822     See in Manteia.
OMIM - 602891
RefSeq - NM_002260
RefSeq Peptide - NP_002251
swissprot - H0YGY2
swissprot - J3KPJ4
swissprot - A0A087WV37
swissprot - P26717
swissprot - F5H518
swissprot - H0YFK4
Ensembl - ENSG00000205809
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Klrc1ENSMUSG00000030167Mus musculus
 Klrc2ENSMUSG00000052736Mus musculus
 Klrc3ENSMUSG00000033027Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC068775.1ENSG0000025564192
KLRC3 / Q07444 / killer cell lectin like receptor C3ENSG0000020581090
KLRC1 / P26715 / killer cell lectin like receptor C1ENSG0000013454577
KLRC4 / O43908 / killer cell lectin like receptor C4ENSG0000018354255
KLRC4-KLRK1 / KLRC4-KLRK1 readthroughENSG0000025581952
KLRD1 / Q13241 / killer cell lectin like receptor D1ENSG0000013453923
KLRK1 / P26718 / killer cell lectin like receptor K1ENSG0000021380917


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR033992  Natural killer cell receptor-like, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002228 natural killer cell mediated immunity IDA
 biological_processGO:0006968 cellular defense response TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0045087 innate immune response TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IDA
 molecular_functionGO:0004888 transmembrane signaling receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0023024 MHC class I protein complex binding IPI
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:1990405 protein antigen binding IDA


Pathways (from Reactome)
Pathway description
DAP12 interactions
DAP12 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000105647 O00459 / PIK3R2 / phosphoinositide-3-kinase regulatory subunit 2  / complex / reaction
 ENSG00000121879 P42336 / PIK3CA / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha  / complex / reaction
 ENSG00000011600 O43914 / TYROBP / TYRO protein tyrosine kinase binding protein  / complex / reaction
 ENSG00000051382 P42338 / PIK3CB / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta  / reaction / complex
 ENSG00000145675 P27986 / PIK3R1 / phosphoinositide-3-kinase regulatory subunit 1  / reaction / complex
 ENSG00000165025 SYK / P43405 / spleen associated tyrosine kinase  / complex / reaction
 ENSG00000010810 FYN / P06241 / FYN proto-oncogene, Src family tyrosine kinase  / complex / reaction
 ENSG00000134539 KLRD1 / Q13241 / killer cell lectin like receptor D1  / complex
 ENSG00000166710 B2M / P61769 / beta-2-microglobulin  / complex
 ENSG00000182866 LCK / P06239 / LCK proto-oncogene, Src family tyrosine kinase  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr